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Review ArticleReview Article

Pharmacology and Therapeutics of Bronchodilators

Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
David R. Sibley, ASSOCIATE EDITOR
Pharmacological Reviews July 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580
Mario Cazzola
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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Clive P. Page
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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Luigino Calzetta
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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M. Gabriella Matera
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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David R. Sibley
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
Roles: ASSOCIATE EDITOR
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Article Information

vol. 64 no. 3 450-504
DOI 
https://doi.org/10.1124/pr.111.004580
PubMed 
22611179

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online July 2, 2012.

Article Versions

  • Earlier version (May 18, 2012 - 09:08).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mario Cazzola,
  2. Clive P. Page,
  3. Luigino Calzetta, and
  4. M. Gabriella Matera
  1. Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
  1. David R. Sibley, ASSOCIATE EDITOR
  1. Address correspondence to:
    Mario Cazzola, Università di Roma ‘Tor Vergata,’ Dipartimento di Medicina Interna, Via Montpellier 1, 00133 Roma, Italy. E-mail: mario.cazzola{at}uniroma2.it
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Pharmacological Reviews: 64 (3)
Pharmacological Reviews
Vol. 64, Issue 3
1 Jul 2012
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Review ArticleReview Article

PHARMACOLOGY AND THERAPEUTICS OF BRONCHODILATORS

Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
Pharmacological Reviews July 1, 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580

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Review ArticleReview Article

PHARMACOLOGY AND THERAPEUTICS OF BRONCHODILATORS

Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
Pharmacological Reviews July 1, 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580
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  • Article
    • Abstract
    • I. Introduction: The Physiological Rationale for Using Bronchodilators
    • II. β-Adrenergic Receptor Agonists
    • III. Muscarinic Acetylcholine Receptor Antagonists
    • IV. Xanthines
    • V. Novel Classes of Bronchodilators
    • VI. Combination Therapy
    • VII. Controversies Surrounding Bronchodilators
    • VIII. The Role of Bronchodilators in the Management of Asthma and Chronic Obstructive Pulmonary Disease
    • IX. The Use of Bronchodilators in Special Populations
    • X. Pharmacogenetics of Airway Obstruction and the Future
    • Authorship Contributions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

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