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Review ArticleReview Article

Chemical Probes of Endocannabinoid Metabolism

Jacqueline L. Blankman and Benjamin F. Cravatt
Eric L. Barker, ASSOCIATE EDITOR
Pharmacological Reviews April 2013, 65 (2) 849-871; DOI: https://doi.org/10.1124/pr.112.006387
Jacqueline L. Blankman
The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
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Benjamin F. Cravatt
The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
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Eric L. Barker
The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
Roles: ASSOCIATE EDITOR
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Article Information

vol. 65 no. 2 849-871
DOI 
https://doi.org/10.1124/pr.112.006387
PubMed 
23512546

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online March 19, 2013.

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jacqueline L. Blankman1 and
  2. Benjamin F. Cravatt
  1. The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
  1. Eric L. Barker, ASSOCIATE EDITOR
  1. Address correspondence to:
    Jacqueline L. Blankman, Abide Therapeutics, 3545 John Hopkins Ct., #250, San Diego, CA 92121, or Benjamin F. Cravatt, The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037. E-mail: jackie{at}abidetx.com (J.L.B.) or cravatt{at}scripps.edu (B.F.C.)
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Pharmacological Reviews: 65 (2)
Pharmacological Reviews
Vol. 65, Issue 2
1 Apr 2013
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Review ArticleReview Article

Endocannabinoid Hydrolase Inhibitors

Jacqueline L. Blankman and Benjamin F. Cravatt
Pharmacological Reviews April 1, 2013, 65 (2) 849-871; DOI: https://doi.org/10.1124/pr.112.006387

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Review ArticleReview Article

Endocannabinoid Hydrolase Inhibitors

Jacqueline L. Blankman and Benjamin F. Cravatt
Pharmacological Reviews April 1, 2013, 65 (2) 849-871; DOI: https://doi.org/10.1124/pr.112.006387
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  • Article
    • Abstract
    • I. Introduction to the Endocannabinoid System
    • II. Identification and Molecular Characterization of Endocannabinoid Hydrolases in the Nervous System
    • III. Development of Endocannabinoid Hydrolase Inhibitors
    • IV. Comparison of the Neurobehavioral Effects of FAAH and MAGL Inhibition
    • V. Non-CB-Mediated Effects
    • VI. Conclusions, Clinical Implications, and Future Directions
    • Acknowledgments
    • Authorship Contributions
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    • Abbreviations
    • References
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