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Review ArticleReview Article

Chemical Probes of Endocannabinoid Metabolism

Jacqueline L. Blankman and Benjamin F. Cravatt
Eric L. Barker, ASSOCIATE EDITOR
Pharmacological Reviews April 2013, 65 (2) 849-871; DOI: https://doi.org/10.1124/pr.112.006387
Jacqueline L. Blankman
The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
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Benjamin F. Cravatt
The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
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Eric L. Barker
The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California
Roles: ASSOCIATE EDITOR
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Pharmacological Reviews: 65 (2)
Pharmacological Reviews
Vol. 65, Issue 2
1 Apr 2013
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Review ArticleReview Article

Endocannabinoid Hydrolase Inhibitors

Jacqueline L. Blankman and Benjamin F. Cravatt
Pharmacological Reviews April 1, 2013, 65 (2) 849-871; DOI: https://doi.org/10.1124/pr.112.006387

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Review ArticleReview Article

Endocannabinoid Hydrolase Inhibitors

Jacqueline L. Blankman and Benjamin F. Cravatt
Pharmacological Reviews April 1, 2013, 65 (2) 849-871; DOI: https://doi.org/10.1124/pr.112.006387
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  • Article
    • Abstract
    • I. Introduction to the Endocannabinoid System
    • II. Identification and Molecular Characterization of Endocannabinoid Hydrolases in the Nervous System
    • III. Development of Endocannabinoid Hydrolase Inhibitors
    • IV. Comparison of the Neurobehavioral Effects of FAAH and MAGL Inhibition
    • V. Non-CB-Mediated Effects
    • VI. Conclusions, Clinical Implications, and Future Directions
    • Acknowledgments
    • Authorship Contributions
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    • Abbreviations
    • References
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