Review ArticleReview Article
Cofactoring and Dimerization of Proteinase-Activated Receptors
Huilan Lin, Allen P. Liu, Thomas H. Smith and JoAnn Trejo
Arthur Christopoulos, ASSOCIATE EDITOR
Pharmacological Reviews October 2013, 65 (4) 1198-1213; DOI: https://doi.org/10.1124/pr.111.004747
Huilan Lin
Department of Pharmacology (H.L., J.T.) and Biomedical Sciences Graduate Program (T.H.S.), School of Medicine, University of California, San Diego, La Jolla, California; and Department of Mechanical and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan (A.P.L.)
Allen P. Liu
Department of Pharmacology (H.L., J.T.) and Biomedical Sciences Graduate Program (T.H.S.), School of Medicine, University of California, San Diego, La Jolla, California; and Department of Mechanical and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan (A.P.L.)
Thomas H. Smith
Department of Pharmacology (H.L., J.T.) and Biomedical Sciences Graduate Program (T.H.S.), School of Medicine, University of California, San Diego, La Jolla, California; and Department of Mechanical and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan (A.P.L.)
JoAnn Trejo
Department of Pharmacology (H.L., J.T.) and Biomedical Sciences Graduate Program (T.H.S.), School of Medicine, University of California, San Diego, La Jolla, California; and Department of Mechanical and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan (A.P.L.)
Arthur Christopoulos
Department of Pharmacology (H.L., J.T.) and Biomedical Sciences Graduate Program (T.H.S.), School of Medicine, University of California, San Diego, La Jolla, California; and Department of Mechanical and Biomedical Engineering, University of Michigan, Ann Arbor, Michigan (A.P.L.)
Roles: ASSOCIATE EDITOR

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In this issue
Review ArticleReview Article
PAR Cofactoring, Dimerization, and Signaling
Huilan Lin, Allen P. Liu, Thomas H. Smith and JoAnn Trejo
Pharmacological Reviews October 1, 2013, 65 (4) 1198-1213; DOI: https://doi.org/10.1124/pr.111.004747
Jump to section
- Article
- Abstract
- I. Introduction
- II. PAR Cofactoring
- III. PAR1 Homodimer
- IV. PAR1 Transactivation of PAR2
- V. PAR1-PAR3 Heterodimer Formation and Signaling
- VI. PAR1-PAR4 Heterodimer Formation
- VII. PAR2 Homo- and Heterodimerization
- VIII. PAR4 Homo- and Heterodimerization
- IX. Conclusions
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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