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Review ArticleReview Article

Insights into Rapid Modulation of Neuroplasticity by Brain Estrogens

Deepak P. Srivastava, Kevin M. Woolfrey and Peter Penzes
Glenda E. Gillies, ASSOCIATE EDITOR
Pharmacological Reviews October 2013, 65 (4) 1318-1350; DOI: https://doi.org/10.1124/pr.111.005272
Deepak P. Srivastava
Department of Neuroscience & Centre for the Cellular Basis of Behaviour, The James Black Centre, Institute of Psychiatry, King's College London, London, United Kingdom (D.P.S.); Department of Physiology (D.P.S., K.M.W., P.P.), Department of Psychiatry and Behavioral Sciences (P.P.), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; and Department of Pharmacology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (K.M.W.)
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Kevin M. Woolfrey
Department of Neuroscience & Centre for the Cellular Basis of Behaviour, The James Black Centre, Institute of Psychiatry, King's College London, London, United Kingdom (D.P.S.); Department of Physiology (D.P.S., K.M.W., P.P.), Department of Psychiatry and Behavioral Sciences (P.P.), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; and Department of Pharmacology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (K.M.W.)
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Peter Penzes
Department of Neuroscience & Centre for the Cellular Basis of Behaviour, The James Black Centre, Institute of Psychiatry, King's College London, London, United Kingdom (D.P.S.); Department of Physiology (D.P.S., K.M.W., P.P.), Department of Psychiatry and Behavioral Sciences (P.P.), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; and Department of Pharmacology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (K.M.W.)
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Glenda E. Gillies
Department of Neuroscience & Centre for the Cellular Basis of Behaviour, The James Black Centre, Institute of Psychiatry, King's College London, London, United Kingdom (D.P.S.); Department of Physiology (D.P.S., K.M.W., P.P.), Department of Psychiatry and Behavioral Sciences (P.P.), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; and Department of Pharmacology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (K.M.W.)
Roles: ASSOCIATE EDITOR
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Article Information

vol. 65 no. 4 1318-1350
DOI 
https://doi.org/10.1124/pr.111.005272
PubMed 
24076546

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online September 27, 2013.

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Deepak P. Srivastava,
  2. Kevin M. Woolfrey, and
  3. Peter Penzes
  1. Department of Neuroscience & Centre for the Cellular Basis of Behaviour, The James Black Centre, Institute of Psychiatry, King's College London, London, United Kingdom (D.P.S.); Department of Physiology (D.P.S., K.M.W., P.P.), Department of Psychiatry and Behavioral Sciences (P.P.),, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; and Department of Pharmacology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (K.M.W.)
  1. Glenda E. Gillies, ASSOCIATE EDITOR
  1. Address correspondence to:
    Deepak P. Srivastava, Department of Neuroscience & Centre for the Cellular Basis of Behaviour, 125 Coldharbour Lane, The James Black Centre, Institute of Psychiatry, King's College London, London, SE5 9NU, UK. E-mail: deepak.srivastava{at}kcl.ac.uk
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Pharmacological Reviews: 65 (4)
Pharmacological Reviews
Vol. 65, Issue 4
1 Oct 2013
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Review ArticleReview Article

Rapid Modulation of Neuroplasticity by Brain Estrogens

Deepak P. Srivastava, Kevin M. Woolfrey and Peter Penzes
Pharmacological Reviews October 1, 2013, 65 (4) 1318-1350; DOI: https://doi.org/10.1124/pr.111.005272

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Review ArticleReview Article

Rapid Modulation of Neuroplasticity by Brain Estrogens

Deepak P. Srivastava, Kevin M. Woolfrey and Peter Penzes
Pharmacological Reviews October 1, 2013, 65 (4) 1318-1350; DOI: https://doi.org/10.1124/pr.111.005272
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  • Article
    • Abstract
    • I. Introduction
    • II. Definitions and Concepts
    • III. Rapid Estrogenic Regulation of Behavior
    • IV. Control of Estrogen Bioavailability in the Brain
    • V. Coupling of Estrogen Receptors to Second Messenger Systems
    • VI. Estrogenic Modulation of Neural Circuits
    • VII. Regulation of Synaptic Function by Estrogens
    • VIII. Molecular Mechanisms Underlying the Remodeling of Dendritic Spines
    • IX. Estrogens and “Two-Step Wiring Plasticity”
    • X. Summary and Future Directions
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

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