Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)

Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)

Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)

Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)

Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)

Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)

Department of Molecular Physiology and Biophysics (M.B., A.W.L, L.A.B., B.E.I.) and Robert M Berne Cardiovascular Research Center (M.B., A.W.L., L.A.B., S.M., B.E.I.), University of Virginia School of Medicine, Charlottesville, Virginia; and Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (S.R.J.)