Review ArticleReview Article
Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers—A New Perspective?
Lucas Treps, Lena-Christin Conradi, Ulrike Harjes and Peter Carmeliet
Yoshihiro Ishikawa, ASSOCIATE EDITOR
Pharmacological Reviews July 2016, 68 (3) 872-887; DOI: https://doi.org/10.1124/pr.116.012492
Lucas Treps
Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, and Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Leuven, Belgium
Lena-Christin Conradi
Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, and Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Leuven, Belgium
Ulrike Harjes
Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, and Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Leuven, Belgium
Peter Carmeliet
Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, and Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Leuven, Belgium
Yoshihiro Ishikawa
Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, and Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Leuven, Belgium
Roles: ASSOCIATE EDITOR

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In this issue
Review ArticleReview Article
Angiogenesis and Endothelial Metabolism
Lucas Treps, Lena-Christin Conradi, Ulrike Harjes and Peter Carmeliet
Pharmacological Reviews July 1, 2016, 68 (3) 872-887; DOI: https://doi.org/10.1124/pr.116.012492
Jump to section
- Article
- Visual Overview
- Abstract
- I. Introduction
- II. Genetic Control of Angiogenesis
- III. Metabolic Control of Angiogenesis
- IV. Endothelial Cell Metabolism Maladaptation in Disease
- V. Pharmacological Targeting of Pathologic Angiogenesis
- VI. Conclusion and Outlook
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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