Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Pharmacological Reviews
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Pharmacological Reviews

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit Pharm Rev on Facebook
  • Follow Pharm Rev on Twitter
  • Follow ASPET on LinkedIn
Review ArticleReview Article
Open Access

Systems Chronotherapeutics

Annabelle Ballesta, Pasquale F. Innominato, Robert Dallmann, David A. Rand and Francis A. Lévi
Stephanie W. Watts, ASSOCIATE EDITOR
Pharmacological Reviews April 2017, 69 (2) 161-199; DOI: https://doi.org/10.1124/pr.116.013441
Annabelle Ballesta
Warwick Medical School (A.B., P.F.I., R.D., F.A.L.) and Warwick Mathematics Institute (A.B., D.A.R.), University of Warwick, Coventry, United Kingdom; Warwick Systems Biology and Infectious Disease Epidemiological Research Centre, Senate House, Coventry, United Kingdom (A.B., P.F.I., R.D., D.A.R., F.A.L.); INSERM–Warwick European Associated Laboratory “Personalising Cancer Chronotherapy through Systems Medicine” (C2SysMed), Unité mixte de Recherche Scientifique 935, Centre National de Recherche Scientifique Campus, Villejuif, France (A.B., P.F.I., R.D., D.A.R., F.A.L.); and Queen Elisabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Cancer Unit, Edgbaston Birmingham, United Kingdom (P.F.I., F.A.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pasquale F. Innominato
Warwick Medical School (A.B., P.F.I., R.D., F.A.L.) and Warwick Mathematics Institute (A.B., D.A.R.), University of Warwick, Coventry, United Kingdom; Warwick Systems Biology and Infectious Disease Epidemiological Research Centre, Senate House, Coventry, United Kingdom (A.B., P.F.I., R.D., D.A.R., F.A.L.); INSERM–Warwick European Associated Laboratory “Personalising Cancer Chronotherapy through Systems Medicine” (C2SysMed), Unité mixte de Recherche Scientifique 935, Centre National de Recherche Scientifique Campus, Villejuif, France (A.B., P.F.I., R.D., D.A.R., F.A.L.); and Queen Elisabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Cancer Unit, Edgbaston Birmingham, United Kingdom (P.F.I., F.A.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert Dallmann
Warwick Medical School (A.B., P.F.I., R.D., F.A.L.) and Warwick Mathematics Institute (A.B., D.A.R.), University of Warwick, Coventry, United Kingdom; Warwick Systems Biology and Infectious Disease Epidemiological Research Centre, Senate House, Coventry, United Kingdom (A.B., P.F.I., R.D., D.A.R., F.A.L.); INSERM–Warwick European Associated Laboratory “Personalising Cancer Chronotherapy through Systems Medicine” (C2SysMed), Unité mixte de Recherche Scientifique 935, Centre National de Recherche Scientifique Campus, Villejuif, France (A.B., P.F.I., R.D., D.A.R., F.A.L.); and Queen Elisabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Cancer Unit, Edgbaston Birmingham, United Kingdom (P.F.I., F.A.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David A. Rand
Warwick Medical School (A.B., P.F.I., R.D., F.A.L.) and Warwick Mathematics Institute (A.B., D.A.R.), University of Warwick, Coventry, United Kingdom; Warwick Systems Biology and Infectious Disease Epidemiological Research Centre, Senate House, Coventry, United Kingdom (A.B., P.F.I., R.D., D.A.R., F.A.L.); INSERM–Warwick European Associated Laboratory “Personalising Cancer Chronotherapy through Systems Medicine” (C2SysMed), Unité mixte de Recherche Scientifique 935, Centre National de Recherche Scientifique Campus, Villejuif, France (A.B., P.F.I., R.D., D.A.R., F.A.L.); and Queen Elisabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Cancer Unit, Edgbaston Birmingham, United Kingdom (P.F.I., F.A.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francis A. Lévi
Warwick Medical School (A.B., P.F.I., R.D., F.A.L.) and Warwick Mathematics Institute (A.B., D.A.R.), University of Warwick, Coventry, United Kingdom; Warwick Systems Biology and Infectious Disease Epidemiological Research Centre, Senate House, Coventry, United Kingdom (A.B., P.F.I., R.D., D.A.R., F.A.L.); INSERM–Warwick European Associated Laboratory “Personalising Cancer Chronotherapy through Systems Medicine” (C2SysMed), Unité mixte de Recherche Scientifique 935, Centre National de Recherche Scientifique Campus, Villejuif, France (A.B., P.F.I., R.D., D.A.R., F.A.L.); and Queen Elisabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Cancer Unit, Edgbaston Birmingham, United Kingdom (P.F.I., F.A.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stephanie W. Watts
Roles: ASSOCIATE EDITOR
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 69 no. 2 161-199
DOI 
https://doi.org/10.1124/pr.116.013441
PubMed 
28351863

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online March 28, 2017.

Copyright & Usage 
Copyright © 2017 by The Author(s) This is an open access article distributed under the CC BY Attribution 4.0 International license.

Author Information

  1. Annabelle Ballesta,
  2. Pasquale F. Innominato,
  3. Robert Dallmann,
  4. David A. Rand, and
  5. Francis A. Lévi
  1. Warwick Medical School (A.B., P.F.I., R.D., F.A.L.) and Warwick Mathematics Institute (A.B., D.A.R.), University of Warwick, Coventry, United Kingdom; Warwick Systems Biology and Infectious Disease Epidemiological Research Centre, Senate House, Coventry, United Kingdom (A.B., P.F.I., R.D., D.A.R., F.A.L.); INSERM–Warwick European Associated Laboratory “Personalising Cancer Chronotherapy through Systems Medicine” (C2SysMed), Unité mixte de Recherche Scientifique 935, Centre National de Recherche Scientifique Campus, Villejuif, France (A.B., P.F.I., R.D., D.A.R., F.A.L.); and Queen Elisabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Cancer Unit, Edgbaston Birmingham, United Kingdom (P.F.I., F.A.L.)
  1. Stephanie W. Watts, ASSOCIATE EDITOR
  1. Address correspondence to:
    Dr. Annabelle Ballesta, University of Warwick–Senate House, Coventry CV4 7AL, United Kingdom. E-mail: a.c.ballesta{at}warwick.ac.uk
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 2018 to March 2023

AbstractFullPdf
Jan 2018015372
Feb 2018313667
Mar 2018121973
Apr 20180489160
May 2018015788
Jun 2018014462
Jul 2018011550
Aug 2018012965
Sep 2018017358
Oct 2018254358
Nov 2018166262
Dec 2018056338
Jan 2019655650
Feb 20191156046
Mar 2019926578
Apr 2019615057
May 2019720978
Jun 20191211953
Jul 2019611662
Aug 2019812778
Oct 2019611289
Nov 2019815057
Dec 20191213052
Jan 2020514643
Feb 2020311434
Mar 2020915551
May 2020912078
Jun 2020810463
Jul 202078254
Aug 202077961
Sep 2020810673
Oct 20201015073
Nov 202017134100
Dec 20201411375
Jan 20211813470
Feb 20212117772
Mar 20211215861
Apr 20211613663
May 202118205124
Jun 2021911261
Jul 20211913579
Aug 2021139947
Sep 20211411442
Oct 202120218102
Nov 20213715699
Dec 20211910463
Jan 20222212275
Feb 20221212459
Mar 20221812680
Apr 202218142124
May 20222010473
Jun 20221711056
Jul 2022309343
Aug 2022179842
Sep 20221514454
Oct 20221013237
Nov 2022139442
Dec 202245837
Jan 202398940
Feb 2023129456
Mar 2023109643

PreviousNext
Back to top

In this issue

Pharmacological Reviews: 69 (2)
Pharmacological Reviews
Vol. 69, Issue 2
1 Apr 2017
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Pharmacological Reviews article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Systems Chronotherapeutics
(Your Name) has forwarded a page to you from Pharmacological Reviews
(Your Name) thought you would be interested in this article in Pharmacological Reviews.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Review ArticleReview Article

Systems Chronotherapeutics

Annabelle Ballesta, Pasquale F. Innominato, Robert Dallmann, David A. Rand and Francis A. Lévi
Pharmacological Reviews April 1, 2017, 69 (2) 161-199; DOI: https://doi.org/10.1124/pr.116.013441

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Review ArticleReview Article

Systems Chronotherapeutics

Annabelle Ballesta, Pasquale F. Innominato, Robert Dallmann, David A. Rand and Francis A. Lévi
Pharmacological Reviews April 1, 2017, 69 (2) 161-199; DOI: https://doi.org/10.1124/pr.116.013441
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Overview
    • Abstract
    • I. Introduction: Systems Approaches to Optimize Chronotherapeutics
    • II. The Circadian Timing System and Its Multilevel Intersubject Variabilities
    • III. Chronotherapeutics
    • IV. Systems Approaches toward Personalized Chronotherapeutics
    • V. Cancer as a Driver for Systems Chronotherapeutics
    • VI. Systems Chronotherapeutics for Other Pathologies
    • VII. CTS Disruption
    • VIII. Conclusions: Expected Benefits and Challenges of Systems Chronotherapeutics
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Review of Natural Language Processing in Pharmacology
  • PHARMACOGENOMICS: Driving Personalized Medicine
  • Potassium Channels in Parkinson's Disease
Show more Review Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Pharmacological Reviews
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacology Research & Perspectives
ISSN 1521-0081 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics