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Review ArticleReview Article

G Protein–Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus

Darren M. Riddy, Philippe Delerive, Roger J. Summers, Patrick M. Sexton and Christopher J. Langmead
Eric L. Barker, ASSOCIATE EDITOR
Pharmacological Reviews January 2018, 70 (1) 39-67; DOI: https://doi.org/10.1124/pr.117.014373
Darren M. Riddy
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (D.M.R., R.J.S., P.M.S., C.J.L.); and Institut de Recherches Servier, Pôle d’Innovation Thérapeutique Métabolisme, Suresnes, France (P.D.)
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Philippe Delerive
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (D.M.R., R.J.S., P.M.S., C.J.L.); and Institut de Recherches Servier, Pôle d’Innovation Thérapeutique Métabolisme, Suresnes, France (P.D.)
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Roger J. Summers
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (D.M.R., R.J.S., P.M.S., C.J.L.); and Institut de Recherches Servier, Pôle d’Innovation Thérapeutique Métabolisme, Suresnes, France (P.D.)
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Patrick M. Sexton
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (D.M.R., R.J.S., P.M.S., C.J.L.); and Institut de Recherches Servier, Pôle d’Innovation Thérapeutique Métabolisme, Suresnes, France (P.D.)
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Christopher J. Langmead
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (D.M.R., R.J.S., P.M.S., C.J.L.); and Institut de Recherches Servier, Pôle d’Innovation Thérapeutique Métabolisme, Suresnes, France (P.D.)
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Eric L. Barker
Roles: ASSOCIATE EDITOR
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Article Information

vol. 70 no. 1 39-67
DOI 
https://doi.org/10.1124/pr.117.014373
PubMed 
29233848

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Received June 22, 2017
  • Accepted September 13, 2017
  • Published online December 12, 2017.

Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Darren M. Riddy,
  2. Philippe Delerive,
  3. Roger J. Summers,
  4. Patrick M. Sexton, and
  5. Christopher J. Langmead
  1. Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (D.M.R., R.J.S., P.M.S., C.J.L.); and Institut de Recherches Servier, Pôle d’Innovation Thérapeutique Métabolisme, Suresnes, France (P.D.)
  1. Eric L. Barker, ASSOCIATE EDITOR
  1. Address correspondence to:
    Dr. Christopher J. Langmead, Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia. E-mail: chris.langmead{at}monash.edu
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Pharmacological Reviews: 70 (1)
Pharmacological Reviews
Vol. 70, Issue 1
1 Jan 2018
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Review ArticleReview Article

GPCR Targets in T2DM

Darren M. Riddy, Philippe Delerive, Roger J. Summers, Patrick M. Sexton and Christopher J. Langmead
Pharmacological Reviews January 1, 2018, 70 (1) 39-67; DOI: https://doi.org/10.1124/pr.117.014373

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Review ArticleReview Article

GPCR Targets in T2DM

Darren M. Riddy, Philippe Delerive, Roger J. Summers, Patrick M. Sexton and Christopher J. Langmead
Pharmacological Reviews January 1, 2018, 70 (1) 39-67; DOI: https://doi.org/10.1124/pr.117.014373
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  • Article
    • Abstract
    • I. Introduction
    • II. G Protein–Coupled Receptors and β-Cell Dysfunction and Insulin Resistance
    • III. G Protein–Coupled Receptors and Obesity-Induced Type 2 Diabetes Mellitus
    • IV. Conclusions and Perspectives
    • Authorship Contributions
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