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History
- Published online March 7, 2019.
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Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Jessie L.-S. Au,
- Roberto A. Abbiati,
- M. Guillaume Wientjes, and
- Ze Lu
- Institute of Quantitative Systems Pharmacology, Carlsbad, California (J.L.-S.A., R.A.A., M.G.W., Z.L.); Department of Pharmaceutical Sciences, University of Oklahoma, Oklahoma City, Oklahoma (J.L.-S.A., R.A.A.); Optimum Therapeutics LLC, Carlsbad, California (J.L.-S.A., M.G.W., Z.L.); and College of Pharmacy, Taipei Medical University, Taipei, Taiwan, Republic of China (J.L.-S.A.)
- Yoshihiro Ishikawa, ASSOCIATE EDITOR
- Address correspondence to:
Jessie L.-S. Au, Institute of Quantitative Systems Pharmacology, 1815 Aston Ave., Suite 107, Carlsbad, CA 92008. E-mail: jau{at}i-qsp.org
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In this issue
QSP to Evaluate Target Site Delivery of Nanomedicines
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- Article
- Abstract
- I. Introduction
- II. Transport from Blood to the Tissue Interstitium
- III. Interactions with the Extracellular Matrix and Cells
- IV. Intracellular Trafficking
- V. Examples of Applying Quantitative Systems Pharmacology to Estimate the Target Site Delivery and Residence of Small Molecule Drugs and Nanosized Medicines
- VI. Interaction of Nanosized Medicine and Proteins to Form Protein Corona
- VII. Unique Regulatory Issues Regarding Nanosized Medicine Products
- VIII. Conclusions and Perspectives
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
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