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History
- Published online March 19, 2019.
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Copyright © 2019 The Author(s). This is an open access article distributed under the CC BY Attribution 4.0 International license.
Author Information
- Gerard Clarke,
- Kiran V. Sandhu,
- Brendan T. Griffin,
- Timothy G. Dinan,
- John F. Cryan, and
- Niall P. Hyland
- APC Microbiome Ireland (G.C., K.V.S., B.T.G., T.G.D., J.F.C., N.P.H.), INFANT Research Centre (G.C.), Department of Psychiatry and Neurobehavioural Science (G.C., T.G.D.), School of Pharmacy (B.T.G.), and Departments of Anatomy and Neuroscience (J.F.C.), Pharmacology and Therapeutics (N.P.H.), and Physiology (N.P.H.), University College Cork, Cork, Ireland
- Charles P. France, ASSOCIATE EDITOR
- Address correspondence to:
Dr. Gerard Clarke, Department of Psychiatry and Neurobehavioural Science and APC Microbiome Ireland, 1.15 Biosciences Building, University College Cork, Cork, Ireland. E-mail: g.clarke{at}ucc.ie
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- Article
- Abstract
- I. Introduction
- II. The Gut Microbiome
- III. Biochemistry of Gut Microbiome Xenobiotic Metabolism
- IV. Factors Influencing the Rate and Extent of Gut Microbiome Xenobiotic Metabolism
- V. The Evolution of Microbial Enzymes for Xenobiotic Metabolism
- VI. Stress-Related Disorders and the Gut Microbiome
- VII. The Gut Microbiome and Xenobiotics in Health and Disease: a Reciprocal Relationship
- VIII. Experimental Approaches in Pharmacomicrobiomics
- IX. Toward Microbiome-Based Treatments and Novel Biotherapeutics
- X. Summary, Conclusions, and Perspectives
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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