Pharmacological Reviews: 71 (4)

October 01, 2019; Volume 71,Issue 4

IUPHAR Nomenclature Report

Open Access
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
Cai Read, Duuamene Nyimanu, Thomas L. Williams, David J. Huggins, Petra Sulentic, Robyn G. C. Macrae, Peiran Yang, Robert C. Glen, Janet J. Maguire and Anthony P. Davenport
Eliot H. Ohlstein, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 467-502; DOI: https://doi.org/10.1124/pr.119.017533

Review Articles

Open Access
Role of Voltage-Gated Sodium Channels in the Mechanism of Ether-Induced Unconsciousness
Nicholas Denomme, Jacob M. Hull and George A. Mashour
Lori L. Isom, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 450-466; DOI: https://doi.org/10.1124/pr.118.016592
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Beyond the Ligand: Extracellular and Transcellular G Protein–Coupled Receptor Complexes in Physiology and Pharmacology
Henry A. Dunn, Cesare Orlandi and Kirill A. Martemyanov
Eric L. Barker, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 503-519; DOI: https://doi.org/10.1124/pr.119.018044
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Druggable Transcriptional Networks in the Human Neurogenic Epigenome
Gerald A. Higgins, Aaron M. Williams, Alex S. Ade, Hasan B. Alam and Brian D. Athey
Lori L. Isom, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 520-538; DOI: https://doi.org/10.1124/pr.119.017681
Open Access
Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure
Lauren B. Arendse, A. H. Jan Danser, Marko Poglitsch, Rhian M. Touyz, John C. Burnett, Catherine Llorens-Cortes, Mario R. Ehlers and Edward D. Sturrock
Eric L. Barker, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 539-570; DOI: https://doi.org/10.1124/pr.118.017129
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Harnessing Ion-Binding Sites for GPCR Pharmacology
Barbara Zarzycka, Saheem A. Zaidi, Bryan L. Roth and Vsevolod Katritch
Eric L. Barker, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 571-595; DOI: https://doi.org/10.1124/pr.119.017863
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Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products
Dongdong Wang, Yang Yang, Yingnan Lei, Nikolay T. Tzvetkov, Xingde Liu, Andy Wai Kan Yeung, Suowen Xu and Atanas G. Atanasov
Qiang Ma, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 596-670; DOI: https://doi.org/10.1124/pr.118.017178
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Challenges and Opportunities for Childhood Cancer Drug Development
Peter J. Houghton and Raushan T. Kurmasheva
Michael M. Gottesman, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 671-697; DOI: https://doi.org/10.1124/pr.118.016972

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