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Encoding, Consolidation, and Renormalization in Depression: Synaptic Homeostasis, Plasticity, and Sleep Integrate Rapid Antidepressant Effects
Tomi Rantamäki and Samuel Kohtala
Markku Koulu, ASSOCIATE EDITOR
Pharmacological Reviews April 2020, 72 (2) 439-465; DOI: https://doi.org/10.1124/pr.119.018697
Tomi Rantamäki
Laboratory of Neurotherapeutics, Drug Research Program, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy (T.R., S.K.) and SleepWell Research Program, Faculty of Medicine (T.R., S.K.), University of Helsinki, Helsinki, Finland
Samuel Kohtala
Laboratory of Neurotherapeutics, Drug Research Program, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy (T.R., S.K.) and SleepWell Research Program, Faculty of Medicine (T.R., S.K.), University of Helsinki, Helsinki, Finland
Markku Koulu
Roles: ASSOCIATE EDITOR

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Review ArticleReview Article
Sleep and Rapid Antidepressant Effects
Tomi Rantamäki and Samuel Kohtala
Pharmacological Reviews April 1, 2020, 72 (2) 439-465; DOI: https://doi.org/10.1124/pr.119.018697
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- Article
- Abstract
- I. Introduction
- II. Synaptic Homeostasis Hypothesis as the Foundation for Encoding, Consolidation, and Renormalization in Depression
- III. The Neurobiological Premise of Major Depression
- IV. Examining Rapid Antidepressant Effects through Encoding, Consolidation, and Renormalization in Depression
- V. Discussion of Encoding, Consolidation, and Renormalization in Depression and Its Implications for Antidepressant Treatments
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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