Review ArticleReview Article
Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease
Melanie A. Felmlee, Robert S. Jones, Vivian Rodriguez-Cruz, Kristin E. Follman and Marilyn E. Morris
Lynette C. Daws, ASSOCIATE EDITOR
Pharmacological Reviews April 2020, 72 (2) 466-485; DOI: https://doi.org/10.1124/pr.119.018762
Melanie A. Felmlee
Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, California (M.A.F.); Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York (R.S.J., V.R.-C., M.E.M.); and Certara Strategic Consulting, Certara USA, Princeton, New Jersey (K.E.F.)
Robert S. Jones
Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, California (M.A.F.); Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York (R.S.J., V.R.-C., M.E.M.); and Certara Strategic Consulting, Certara USA, Princeton, New Jersey (K.E.F.)
Vivian Rodriguez-Cruz
Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, California (M.A.F.); Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York (R.S.J., V.R.-C., M.E.M.); and Certara Strategic Consulting, Certara USA, Princeton, New Jersey (K.E.F.)
Kristin E. Follman
Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, California (M.A.F.); Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York (R.S.J., V.R.-C., M.E.M.); and Certara Strategic Consulting, Certara USA, Princeton, New Jersey (K.E.F.)
Marilyn E. Morris
Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, California (M.A.F.); Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York (R.S.J., V.R.-C., M.E.M.); and Certara Strategic Consulting, Certara USA, Princeton, New Jersey (K.E.F.)
Lynette C. Daws
Roles: ASSOCIATE EDITOR

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In this issue
Review ArticleReview Article
Monocarboxylate Transporters in Health and Disease
Melanie A. Felmlee, Robert S. Jones, Vivian Rodriguez-Cruz, Kristin E. Follman and Marilyn E. Morris
Pharmacological Reviews April 1, 2020, 72 (2) 466-485; DOI: https://doi.org/10.1124/pr.119.018762
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- Article
- Abstract
- I. Introduction
- II. Structure and Function
- III. Expression and Localization
- IV. Substrates and Inhibitors
- V. Regulation and Development
- VI. Monocarboxylate Transporters in Health and Disease
- VII. Findings from the Use of Genetically-Modified Mct Rodent Models
- VIII. Conclusions and Future Studies
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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