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Review ArticleReview Article
Open Access

RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges

Ai-Ming Yu, Young Hee Choi and Mei-Juan Tu
RHIAN M. TOUYZ, ASSOCIATE EDITOR
Pharmacological Reviews October 2020, 72 (4) 862-898; DOI: https://doi.org/10.1124/pr.120.019554
Ai-Ming Yu
Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, California (A.-M.Y., Y.H.C., M.-J.T.) and College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyonggi-do, Republic of Korea (Y.H.C.)
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Young Hee Choi
Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, California (A.-M.Y., Y.H.C., M.-J.T.) and College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyonggi-do, Republic of Korea (Y.H.C.)
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Mei-Juan Tu
Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, California (A.-M.Y., Y.H.C., M.-J.T.) and College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyonggi-do, Republic of Korea (Y.H.C.)
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RHIAN M. TOUYZ
Roles: ASSOCIATE EDITOR
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Article Information

vol. 72 no. 4 862-898
DOI 
https://doi.org/10.1124/pr.120.019554
PubMed 
32929000

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online September 14, 2020.

Copyright & Usage 
Copyright © 2020 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license.

Author Information

  1. Ai-Ming Yu,
  2. Young Hee Choi, and
  3. Mei-Juan Tu
  1. Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, California (A.-M.Y., Y.H.C., M.-J.T.) and College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyonggi-do, Republic of Korea (Y.H.C.)
  1. RHIAN M. TOUYZ, ASSOCIATE EDITOR
  1. Address correspondence to:
    Dr. Ai-Ming Yu, Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, 2700 Stockton Blvd. Suite 2132, Oak Park Research Building, Sacramento, CA 95817. E-mail: aimyu{at}ucdavis.edu; or Dr. Young Hee Choi, College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, 32 Dongguk-lo, Ilsandong-gu, Goyang-si, Gyeonggi-do 10326, Republic of Korea. E-mail: choiyh{at}dongguk.edu
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Pharmacological Reviews: 72 (4)
Pharmacological Reviews
Vol. 72, Issue 4
1 Oct 2020
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Review ArticleReview Article

RNA-Based Therapies

Ai-Ming Yu, Young Hee Choi and Mei-Juan Tu
Pharmacological Reviews October 1, 2020, 72 (4) 862-898; DOI: https://doi.org/10.1124/pr.120.019554

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Review ArticleReview Article

RNA-Based Therapies

Ai-Ming Yu, Young Hee Choi and Mei-Juan Tu
Pharmacological Reviews October 1, 2020, 72 (4) 862-898; DOI: https://doi.org/10.1124/pr.120.019554
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  • Article
    • Visual Overview
    • Abstract
    • I. Introduction
    • II. Classification and General Features of RNA-Based Therapeutics
    • III. RNAs as Therapeutic Drugs
    • IV. RNAs as Therapeutic Targets for Small Molecules
    • V. Conclusions and Perspectives
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