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Open Access

Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms

Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Michael Nader, ASSOCIATE EDITOR
Pharmacological Reviews January 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056
Antonio Inserra
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
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Danilo De Gregorio
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
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Gabriella Gobbi
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
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Michael Nader
Roles: ASSOCIATE EDITOR
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Article Information

vol. 73 no. 1 202-277
DOI 
https://doi.org/10.1124/pharmrev.120.000056
PubMed 
33328244

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online December 16, 2020.

Copyright & Usage 
Copyright © 2020 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license.

Author Information

  1. Antonio Inserra,
  2. Danilo De Gregorio, and
  3. Gabriella Gobbi
  1. Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
  1. Michael Nader, ASSOCIATE EDITOR
  1. Address correspondence to:
    Gabriella Gobbi, Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, 1033, Av. des Pins Ouest, Montreal, QC H3A 1A1, Canada. E-mail: gabriella.gobbi{at}mcgill.ca
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Pharmacological Reviews: 73 (1)
Pharmacological Reviews
Vol. 73, Issue 1
1 Jan 2021
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Review ArticleReview Article

Psychedelics in Psychiatry: Therapeutic Mechanisms

Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Pharmacological Reviews January 1, 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056

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Review ArticleReview Article

Psychedelics in Psychiatry: Therapeutic Mechanisms

Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Pharmacological Reviews January 1, 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056
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  • Article
    • Abstract
    • I. Introduction
    • II. Psychedelic Compounds as Neuroplastic Agents
    • III. Psychedelic Compounds as Immunomodulatory and Anti-Inflammatory Agents
    • IV. Psychedelic Compounds as Modulators of Neurotransmitter Systems
    • V. Biased Signaling, Biased Phosphoproteomics, and Psychedelic Compounds
    • VI. Going Beyond Receptors: Neuronal Circuits Activated by Psychedelic Drugs
    • VII. Effects of Psychedelics on Sleep
    • VIII. Long-Term Neurobiological and Psychological Effects of Psychedelic Compounds
    • IX. Side Effects of Psychedelic Compounds
    • X. Recommendations for Future Research
    • XI. Conclusion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
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