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Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms

Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Michael Nader, ASSOCIATE EDITOR
Pharmacological Reviews January 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056
Antonio Inserra
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
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Danilo De Gregorio
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
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Gabriella Gobbi
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
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Michael Nader
Roles: ASSOCIATE EDITOR
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Pharmacological Reviews: 73 (1)
Pharmacological Reviews
Vol. 73, Issue 1
1 Jan 2021
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Review ArticleReview Article

Psychedelics in Psychiatry: Therapeutic Mechanisms

Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Pharmacological Reviews January 1, 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056

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Review ArticleReview Article

Psychedelics in Psychiatry: Therapeutic Mechanisms

Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Pharmacological Reviews January 1, 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056
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  • Article
    • Abstract
    • I. Introduction
    • II. Psychedelic Compounds as Neuroplastic Agents
    • III. Psychedelic Compounds as Immunomodulatory and Anti-Inflammatory Agents
    • IV. Psychedelic Compounds as Modulators of Neurotransmitter Systems
    • V. Biased Signaling, Biased Phosphoproteomics, and Psychedelic Compounds
    • VI. Going Beyond Receptors: Neuronal Circuits Activated by Psychedelic Drugs
    • VII. Effects of Psychedelics on Sleep
    • VIII. Long-Term Neurobiological and Psychological Effects of Psychedelic Compounds
    • IX. Side Effects of Psychedelic Compounds
    • X. Recommendations for Future Research
    • XI. Conclusion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
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