Review ArticleReview Article
Open Access
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms
Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Michael Nader, ASSOCIATE EDITOR
Pharmacological Reviews January 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056
Antonio Inserra
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
Danilo De Gregorio
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
Gabriella Gobbi
Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
Michael Nader
Roles: ASSOCIATE EDITOR

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Review ArticleReview Article
Psychedelics in Psychiatry: Therapeutic Mechanisms
Antonio Inserra, Danilo De Gregorio and Gabriella Gobbi
Pharmacological Reviews January 1, 2021, 73 (1) 202-277; DOI: https://doi.org/10.1124/pharmrev.120.000056
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- Article
- Abstract
- I. Introduction
- II. Psychedelic Compounds as Neuroplastic Agents
- III. Psychedelic Compounds as Immunomodulatory and Anti-Inflammatory Agents
- IV. Psychedelic Compounds as Modulators of Neurotransmitter Systems
- V. Biased Signaling, Biased Phosphoproteomics, and Psychedelic Compounds
- VI. Going Beyond Receptors: Neuronal Circuits Activated by Psychedelic Drugs
- VII. Effects of Psychedelics on Sleep
- VIII. Long-Term Neurobiological and Psychological Effects of Psychedelic Compounds
- IX. Side Effects of Psychedelic Compounds
- X. Recommendations for Future Research
- XI. Conclusion
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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