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Review ArticleReview Article

Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors

Roger L. Papke and Nicole A. Horenstein
Habibeh Khoshbouei, ASSOCIATE EDITOR
Pharmacological Reviews July 2021, 73 (3) 1118-1149; DOI: https://doi.org/10.1124/pharmrev.120.000097
Roger L. Papke
Departments of Pharmacology and Therapeutics (R.L.P) and Chemistry (N.A.H.), University of Florida, Gainesville, FL
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Nicole A. Horenstein
Departments of Pharmacology and Therapeutics (R.L.P) and Chemistry (N.A.H.), University of Florida, Gainesville, FL
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Habibeh Khoshbouei
Roles: ASSOCIATE EDITOR
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Article Information

vol. 73 no. 3 1118-1149
DOI 
https://doi.org/10.1124/pharmrev.120.000097
PubMed 
34301823

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online July 22, 2021.

Copyright & Usage 
Copyright © 2021 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Roger L. Papke and
  2. Nicole A. Horenstein
  1. Departments of Pharmacology and Therapeutics (R.L.P) and Chemistry (N.A.H.), University of Florida, Gainesville, FL
  1. Habibeh Khoshbouei, ASSOCIATE EDITOR
  1. Address correspondence to:
    Roger L. Papke, Department of Pharmacology and Therapeutics, University of Florida, P.O. Box 100267, Gainesville, FL 32610-0267. E-mail: rlpapke{at}ufl.edu
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Pharmacological Reviews: 73 (3)
Pharmacological Reviews
Vol. 73, Issue 3
1 Jul 2021
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Review ArticleReview Article

Therapeutic Targeting of α7 nAChR

Roger L. Papke and Nicole A. Horenstein
Pharmacological Reviews July 1, 2021, 73 (3) 1118-1149; DOI: https://doi.org/10.1124/pharmrev.120.000097

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Review ArticleReview Article

Therapeutic Targeting of α7 nAChR

Roger L. Papke and Nicole A. Horenstein
Pharmacological Reviews July 1, 2021, 73 (3) 1118-1149; DOI: https://doi.org/10.1124/pharmrev.120.000097
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  • Article
    • Abstract
    • I. Introduction
    • II. Diversity of Nicotinic Acetylcholine Receptor
    • III. α7 Receptors as Therapeutic Targets
    • IV. α7-Selective Agonists
    • V. α7-Positive Allosteric Modulators
    • VI. Silent Agonists
    • VII. α7 Antagonists
    • VIII. Discussion and Conclusions
    • Acknowledgments
    • Appendix
    • Expression in Xenopus Oocytes
    • Two-Electrode Voltage-Clamp Electrophysiology
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
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  • eLetters
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