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In this issue
Parkinson Disease Molecular Mechanisms and Neuroprotection
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- Article
- Visual Overview
- Abstract
- I. Introduction
- II. Current Treatment Is Symptomatic
- III. Challenges to the Identification of Disease-Modifying Therapies
- IV. Biomarkers
- V. Genetics of Parkinson Disease
- VI. Environmental Contributors to Disease Progression
- VII. Targeting Pathways that Promote Clearance of α-Synuclein
- VIII. Mitochondrial Pathways to Neuroprotection
- IX. Mitochondrial-Based Therapeutic Approaches
- X. Interventions to Counter α-Synuclein Toxicity
- XI. Therapeutic Avenues from Neuroinflammatory Pathways
- XII. Targeting Altered Protein Translation
- XIII. Maintenance of Neural Calcium Homeostasis for Neuroprotection
- XIV. Regulation of Neuronal Oxidative and Nitrosative Stress
- XV. Repairing Defects in Synaptic Dysfunctions
- XVI. Neurotrophic Factors May Repair Dopaminergic Neurons
- XVII. Conclusion
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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