Review ArticleReview Article
Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics
Krishna D. B. Anapindi, Elena V. Romanova, James W. Checco and Jonathan V. Sweedler
Vivian Hook, ASSOCIATE EDITOR
Pharmacological Reviews July 2022, 74 (3) 662-679; DOI: https://doi.org/10.1124/pharmrev.121.000423
Krishna D. B. Anapindi
Department of Chemistry and the Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois (K.D.B.A., E.V.R., J.V.S.) and Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska (J.W.C.)
Elena V. Romanova
Department of Chemistry and the Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois (K.D.B.A., E.V.R., J.V.S.) and Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska (J.W.C.)
James W. Checco
Department of Chemistry and the Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois (K.D.B.A., E.V.R., J.V.S.) and Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska (J.W.C.)
Jonathan V. Sweedler
Department of Chemistry and the Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois (K.D.B.A., E.V.R., J.V.S.) and Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska (J.W.C.)
Vivian Hook
Roles: ASSOCIATE EDITOR

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In this issue
Review ArticleReview Article
Mass Spectrometry for Neuropeptide Discovery
Krishna D. B. Anapindi, Elena V. Romanova, James W. Checco and Jonathan V. Sweedler
Pharmacological Reviews July 1, 2022, 74 (3) 662-679; DOI: https://doi.org/10.1124/pharmrev.121.000423
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- Article
- Visual Overview
- Abstract
- I. Introduction: A Century of Neuropeptide/Hormone Discovery: Where Are We and Where Are We Going?
- II. What Are Neuropeptides and Peptide Hormones?
- III. Methods of Neuropeptide Discovery and Characterization
- IV. From Discovery to Function
- V. Unusual Routes to Peptide Formation and Function
- VI. The Rise of Biologics: Therapeutic Peptides
- VII. Conclusions
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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