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Turn On, Tune In, Turnover! Target Biology Impacts In Vivo Potency, Efficacy, and Clearance

Johan Gabrielsson and Stephan Hjorth
Paul Insel, ASSOCIATE EDITOR
Pharmacological Reviews May 2023, 75 (3) 416-462; DOI: https://doi.org/10.1124/pharmrev.121.000524

Article Information

vol. 75 no. 3 416-462
DOI 
https://doi.org/10.1124/pharmrev.121.000524
PubMed 
36627211
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Received October 31, 2021
  • Accepted November 18, 2022
  • Published online April 21, 2023.

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Copyright & Usage 
Copyright © 2023 by The Author(s) This is an open access article distributed under the CC BY Attribution 4.0 International license.

Author Information

  1. Johan Gabrielsson and
  2. Stephan Hjorth
  1. MedDoor AB, Gothenburg, Sweden (J.G.) and Pharmacilitator AB, Vallda, Sweden (S.H.)
  1. Paul Insel, ASSOCIATE EDITOR
  1. Address correspondence to:
    John Gabrielsson, MedDoor AB, Engelbrektsgatan 5, 41127 Gothenburg, Sweden. E-mail: Professor.Gabrielsson{at}gmail.com
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Jan 2023370031
Feb 2023216010
Mar 20232251458
Apr 2023761827131
May 2023383767124
Jun 202315263262
Jul 20232897984
Aug 20231819050
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Target Turnover Impacts Potency, Efficacy, and Clearance

Johan Gabrielsson and Stephan Hjorth
Pharmacological Reviews May 1, 2023, 75 (3) 416-462; DOI: https://doi.org/10.1124/pharmrev.121.000524
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