Table of Contents

Review Articles

• Open Access

  G Protein-Coupled Receptor Pharmacology—Insights from Mass Spectrometry

  Hsin-Yung Yen, Ali Jazayeri and Carol V. Robinson

  Gunnar Schulte, ASSOCIATE EDITOR

  Pharmacological Reviews May 2023, 75 (3) 397-415; DOI: https://doi.org/10.1124/pharmrev.120.000237
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  Open Access

  Turn On, Tune In, Turnover! Target Biology Impacts In Vivo Potency, Efficacy, and Clearance

  Johan Gabrielsson and Stephan Hjorth

  Paul Insel, ASSOCIATE EDITOR

  Pharmacological Reviews May 2023, 75 (3) 416-462; DOI: https://doi.org/10.1124/pharmrev.121.000524
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  Open Access

  Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity

  Charlotte A. Hoogstraten, Jonathan J. Lyon, Jan A.M. Smeitink, Frans G.M. Russel and Tom J.J. Schirris

  John Schuetz, ASSOCIATE EDITOR

  Pharmacological Reviews May 2023, 75 (3) 463-486; DOI: https://doi.org/10.1124/pharmrev.122.000568
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  Open Access

  Pharmacological Inhibition of the NLRP3 Inflammasome: Structure, Molecular Activation, and Inhibitor-NLRP3 Interaction

  Qiang Ma

  John Schuetz, ASSOCIATE EDITOR

  Pharmacological Reviews May 2023, 75 (3) 487-520; DOI: https://doi.org/10.1124/pharmrev.122.000629
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  You have access

  Sulfotransferase 2B1b, Sterol Sulfonation, and Disease

  Ian Cook and Thomas S. Leyh

  Stephen Alexander, ASSOCIATE EDITOR

  Pharmacological Reviews May 2023, 75 (3) 521-531; DOI: https://doi.org/10.1124/pharmrev.122.000679
• You have access

  Understanding the Neural Mechanisms of General Anesthesia from Interaction with Sleep–Wake State: A Decade of Discovery

  Wei-Wei Bao, Shan Jiang, Wei-Min Qu, Wen-Xian Li, Chang-Hong Miao and Zhi-Li Huang

  Lynette Daws, ASSOCIATE EDITOR

  Pharmacological Reviews May 2023, 75 (3) 532-553; DOI: https://doi.org/10.1124/pharmrev.122.000717