Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Pharmacological Reviews
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Pharmacological Reviews

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit Pharm Rev on Facebook
  • Follow Pharm Rev on Twitter
  • Follow ASPET on LinkedIn
Review ArticleReview Article

Advances in Nanozymes as a Paradigm for Viral Diagnostics and Therapy

Garima Sharma, Srijan Chatterjee, Chiranjib Chakraborty and Jin-Chul Kim
Martin Michel, Associate Editor
Pharmacological Reviews July 2023, 75 (4) 739-757; DOI: https://doi.org/10.1124/pharmrev.122.000719
Garima Sharma
Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Republic of Korea (G.S., J.-C.K.) and Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, India (S.C., C.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Garima Sharma
Srijan Chatterjee
Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Republic of Korea (G.S., J.-C.K.) and Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, India (S.C., C.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Srijan Chatterjee
Chiranjib Chakraborty
Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Republic of Korea (G.S., J.-C.K.) and Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, India (S.C., C.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Chiranjib Chakraborty
Jin-Chul Kim
Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Republic of Korea (G.S., J.-C.K.) and Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, India (S.C., C.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jin-Chul Kim
Martin Michel
Roles: Associate Editor
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Visual Overview

Figure
  • Download figure
  • Open in new tab
  • Download powerpoint

Abstract

Over the past few decades, humankind has constantly encountered new viral species that create havoc in the socioeconomic balance worldwide. Among the method to combat these novel viral infections, fast and point-of-care diagnosis is of prime importance to contain the spreading of viral infections. However, most sensitive diagnostic systems for viral infections are time-consuming and require well-trained professionals, making it difficult for the patients. In recent years nanozymes emerged as promising therapeutic and fast diagnostic tools due to their multienzyme-like catalytic performance. Nanozymes can be designed using inorganic or organic components with tailorable physicochemical surface properties, enabling the attachment of various molecules and species on the surface of the nanozyme for specific recognition. In addition to the composition, the multienzyme-like catalytic performance can be modulated by the shape and size of the nanoparticles. Due to their multicatalytic abilities, nanozymes can be used for fast diagnosis and therapy for viral infections. Here we attempt to focus on the insights and recent explorations on the advances in designing various types of nanozymes as a theranostic tool for viral infections. Thus, this review intends to generate interest in the clinical translation of nanozymes as a theranostic tool for viral infections by providing knowledge about the multidisciplinary potential of nanozyme.

Significance Statement The multienzyme-like properties of nanozymes suggest their role in diagnosing and treating various diseases. Although the potential roles of nanozymes for various viral infections have been studied in the last few decades, no review provides recent explorations on designing various types of nanozymes for the detection and treatment of viral infections. This review provides insights into designing nanozymes to diagnose and treat viral infections, assisting future researchers in developing clinically translatable nanozymes to combat novel viral infections.

Footnotes

    • Received August 19, 2022.
    • Revision received January 9, 2023.
    • Accepted January 17, 2023.
  • This research was funded by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education [Grants 2022R1I1A1A01065269 and 2018R1A6A1A03025582] and the Korea government (MSIT) [Grant 2022R1A2C2003353].

  • No author has an actual or perceived conflict of interest with the contents of this article.

  • dx.doi.org/10.1124/pharmrev.122.000719.

  • Copyright © 2023 by The American Society for Pharmacology and Experimental Therapeutics
View Full Text

PharmRev articles become freely available 12 months after publication, and remain freely available for 5 years. 

Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page. 

 

  • Click here for information on institutional subscriptions.
  • Click here for information on individual ASPET membership.

 

Log in using your username and password

Forgot your user name or password?

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.
PreviousNext
Back to top

In this issue

Pharmacological Reviews: 75 (4)
Pharmacological Reviews
Vol. 75, Issue 4
1 Jul 2023
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Pharmacological Reviews article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Advances in Nanozymes as a Paradigm for Viral Diagnostics and Therapy
(Your Name) has forwarded a page to you from Pharmacological Reviews
(Your Name) thought you would be interested in this article in Pharmacological Reviews.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Review ArticleReview Article

Nanozymes for Viral Diagnosis and Therapy

Garima Sharma, Srijan Chatterjee, Chiranjib Chakraborty and Jin-Chul Kim
Pharmacological Reviews July 1, 2023, 75 (4) 739-757; DOI: https://doi.org/10.1124/pharmrev.122.000719

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Review ArticleReview Article

Nanozymes for Viral Diagnosis and Therapy

Garima Sharma, Srijan Chatterjee, Chiranjib Chakraborty and Jin-Chul Kim
Pharmacological Reviews July 1, 2023, 75 (4) 739-757; DOI: https://doi.org/10.1124/pharmrev.122.000719
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Overview
    • Abstract
    • I. Introduction
    • II. Nanozymes Based on Composition
    • III. Nanozymes Based on Enzymatic Activities
    • IV. Role of Nanozymes as a Diagnostic and Therapeutic Agent Against Viral Infections
    • V. Limitations of Using Nanozymes as a Therapeutic Agent
    • VI. Conclusion
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • PROKINETICIN RECEPTORS AS THERAPEUTIC TARGETS
  • ASO and siRNA drugs for systemic diseases of liver origin
  • β-Arrestins: Structure, Function, and Physiology
Show more Review article

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Pharmacological Reviews
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacology Research & Perspectives
ISSN 1521-0081 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics