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Turn on, tune in, turnover! Target biology impacts in vivo potency, efficacy, and clearance

Johan Gabrielsson and Stephan Hjorth
Pharmacological Reviews January 10, 2023, PHARMREV-AR-2021-000524; DOI: https://doi.org/10.1124/pharmrev.121.000524

Article Information

PHARMREV-AR-2021-000524
DOI 
https://doi.org/10.1124/pharmrev.121.000524
PubMed 
36627211
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online January 10, 2023.
Copyright & Usage 
© 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution CC BY License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

Author Information

  1. Johan Gabrielsson1,* and
  2. Stephan Hjorth2
  1. 1MedDoor AB, Sweden
  2. 2Integrative Research Laboratories AB, Sweden
  1. ↵* Corresponding Author:
    Johan Gabrielsson, MedDoor AB, Engelbrektsgatan 5, Gothenburg, N/A, 41127, Sweden. E-mail: 031.7117075{at}telia.com

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OtherReview Article

Target turnover impacts potency, efficacy and clearance

Johan Gabrielsson and Stephan Hjorth
Pharmacological Reviews January 10, 2023, PHARMREV-AR-2021-000524; DOI: https://doi.org/10.1124/pharmrev.121.000524
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