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Modeling Pharmacokinetic Natural Product–Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach
Emily J. Cox, Dan-Dan Tian, John D. Clarke, Allan E. Rettie, Jashvant D. Unadkat, Kenneth E. Thummel, Jeannine S. McCune and Mary F. Paine
Hyunyoung Jeong, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 847-859; DOI: https://doi.org/10.1124/pharmrev.120.000106
Open Access
Viral G Protein–Coupled Receptors: Attractive Targets for Herpesvirus-Associated Diseases
Timo W. M. De Groof, Elizabeth G. Elder, Marco Siderius, Raimond Heukers, John H. Sinclair and Martine J. Smit
Gunnar Schulte, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 828-846; DOI: https://doi.org/10.1124/pharmrev.120.000186
Open Access
Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics
Peter Garred, Andrea J. Tenner and Tom E. Mollnes
Finn Olav Levy, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 792-827; DOI: https://doi.org/10.1124/pharmrev.120.000072
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Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications
Jaclyn N. Highland, Panos Zanos, Lace M. Riggs, Polymnia Georgiou, Sarah M. Clark, Patrick J. Morris, Ruin Moaddel, Craig J. Thomas, Carlos A. Zarate, Edna F. R. Pereira and Todd D. Gould
Robert Dantzer, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 763-791; DOI: https://doi.org/10.1124/pharmrev.120.000149
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Sex- and Gender-Based Pharmacological Response to Drugs
Franck Mauvais-Jarvis, Heiner K. Berthold, Ilaria Campesi, Juan-Jesus Carrero, Santosh Dhakal, Flavia Franconi, Ioanna Gouni-Berthold, Mark L. Heiman, Alexandra Kautzky-Willer, Sabra L. Klein, Anne Murphy, Vera Regitz-Zagrosek, Karen Reue and Joshua B. Rubin
Eric Barker, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 730-762; DOI: https://doi.org/10.1124/pharmrev.120.000206
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Correction to “Cognitive Effects of MDMA in Laboratory Animals: A Systematic Review Focusing on Dose”
Pharmacological Reviews April 2021, 73 (2) 729; DOI: https://doi.org/10.1124/pr.118.017087err
Open Access
Rescuing the Last-Line Polymyxins: Achievements and Challenges
Sue C. Nang, Mohammad A. K. Azad, Tony Velkov, Qi (Tony) Zhou and Jian Li
Eric Barker, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 679-728; DOI: https://doi.org/10.1124/pharmrev.120.000020
Open Access
Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species
B. D. van Groen, J. Nicolaï, A. C. Kuik, S. Van Cruchten, E. van Peer, A. Smits, S. Schmidt, S. N. de Wildt, K. Allegaert, L. De Schaepdrijver, P. Annaert and J. Badée
Hyunyoung Jeong, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 597-678; DOI: https://doi.org/10.1124/pharmrev.120.000071
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Evidence for Modulation of Substance Use Disorders by the Gut Microbiome: Hidden in Plain Sight
Mariana Angoa-Pérez and Donald M. Kuhn
Charles France, ASSOCIATE EDITOR

Pharmacological Reviews April 2021, 73 (2) 571-596; DOI: https://doi.org/10.1124/pharmrev.120.000144
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Correction to “Pharmacological Manipulation of Translation as a Therapeutic Target for Chronic Pain”
Pharmacological Reviews January 2021, 73 (1) 570; DOI: https://doi.org/10.1124/pharmrev.120.000030err

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