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Pharmacological Reviews

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Latest Articles

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    Goods and bads of endocannabinoid system as a therapeutic target: Lessons learned after 30 years
    Mauro Maccarrone, Vincenzo Di Marzo, Juerg Gertsch, Uwe Grether, Allyn C. Howlett, Tian Hua, Alexandros Makriyannis, Daniele Piomelli, Natsuo Ueda and Mario van der Stelt
    Pharmacological Reviews May 10, 2023, PHARMREV-AR-2022-000600; DOI: https://doi.org/10.1124/pharmrev.122.000600
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    Paradoxes of cellular SUMOylation regulation: a role of biomolecular condensates?
    Xiaodong Cheng, Wenli Yang, Wei Lin and Fang Mei
    Pharmacological Reviews May 3, 2023, PHARMREV-AR-2022-000784; DOI: https://doi.org/10.1124/pharmrev.122.000784
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    Pharmacological regulation of endoplasmic reticulum structure and calcium dynamics: importance for neurodegenerative diseases
    Ilmari Parkkinen, Anna Their, Muhammad Yasir Asghar, Sreesha Sree, Eija Jokitalo and Mikko Airavaara
    Pharmacological Reviews May 1, 2023, PHARMREV-AR-2022-000701; DOI: https://doi.org/10.1124/pharmrev.122.000701
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    Understanding the Neural Mechanisms of General Anesthesia from Interaction with Sleep–Wake State: A Decade of Discovery
    Wei-Wei Bao, Shan Jiang, Wei-Min Qu, Wen-Xian Li, Chang-Hong Miao and Zhi-Li Huang
    Lynette Daws, ASSOCIATE EDITOR
    Pharmacological Reviews May 2023, 75 (3) 532-553; DOI: https://doi.org/10.1124/pharmrev.122.000717
  • Turn On, Tune In, Turnover! Target Biology Impacts In Vivo Potency, Efficacy, and Clearance
    Open Access
    Turn On, Tune In, Turnover! Target Biology Impacts In Vivo Potency, Efficacy, and Clearance
    Johan Gabrielsson and Stephan Hjorth
    Paul Insel, ASSOCIATE EDITOR
    Pharmacological Reviews May 2023, 75 (3) 416-462; DOI: https://doi.org/10.1124/pharmrev.121.000524
  • Pharmacological Inhibition of the NLRP3 Inflammasome: Structure, Molecular Activation, and Inhibitor-NLRP3 Interaction
    Open Access
    Pharmacological Inhibition of the NLRP3 Inflammasome: Structure, Molecular Activation, and Inhibitor-NLRP3 Interaction
    Qiang Ma
    John Schuetz, ASSOCIATE EDITOR
    Pharmacological Reviews May 2023, 75 (3) 487-520; DOI: https://doi.org/10.1124/pharmrev.122.000629
  • Open Access
    G Protein-Coupled Receptor Pharmacology—Insights from Mass Spectrometry
    Hsin-Yung Yen, Ali Jazayeri and Carol V. Robinson
    Gunnar Schulte, ASSOCIATE EDITOR
    Pharmacological Reviews May 2023, 75 (3) 397-415; DOI: https://doi.org/10.1124/pharmrev.120.000237
  • Sulfotransferase 2B1b, Sterol Sulfonation, and Disease
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    Sulfotransferase 2B1b, Sterol Sulfonation, and Disease
    Ian Cook and Thomas S. Leyh
    Stephen Alexander, ASSOCIATE EDITOR
    Pharmacological Reviews May 2023, 75 (3) 521-531; DOI: https://doi.org/10.1124/pharmrev.122.000679
  • Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity
    Open Access
    Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity
    Charlotte A. Hoogstraten, Jonathan J. Lyon, Jan A.M. Smeitink, Frans G.M. Russel and Tom J.J. Schirris
    John Schuetz, ASSOCIATE EDITOR
    Pharmacological Reviews May 2023, 75 (3) 463-486; DOI: https://doi.org/10.1124/pharmrev.122.000568
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    β-Arrestins: Structure, Function, Physiology, and Pharmacological Perspectives
    Jürgen Wess, Antwi-Boasiako Oteng, Osvaldo Rivera-Gonzalez, Eugenia V. Gurevich and Vsevolod V. Gurevich
    Pharmacological Reviews April 7, 2023, PHARMREV-AR-2021-000302; DOI: https://doi.org/10.1124/pharmrev.121.000302

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