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Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development—Current State-of-the-Art and Future Perspectives
Sonia Youhanna, Aurino M. Kemas, Lena Preiss, Yitian Zhou, Joanne X. Shen, Selgin D. Cakal, Francesco S. Paqualini, Sravan K. Goparaju, Reza Zandi Shafagh, Johan Ulrik Lind, Carl M. Sellgren and Volker M. Lauschke
Gunnar Schulte, ASSOCIATE EDITOR

Pharmacological Reviews January 2022, 74 (1) 141-206; DOI: https://doi.org/10.1124/pharmrev.120.000238
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Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review
Céline Nicolas, Natalie E. Zlebnik, Mehdi Farokhnia, Lorenzo Leggio, Satoshi Ikemoto and Yavin Shaham
Michael Nader, ASSOCIATE EDITOR

Pharmacological Reviews January 2022, 74 (1) 119-140; DOI: https://doi.org/10.1124/pharmrev.121.000367
Open Access
Inhaled Medicines: Past, Present, and Future
Sandra Anderson, Paul Atkins, Per Bäckman, David Cipolla, Andrew Clark, Evangelia Daviskas, Bernd Disse, Plamena Entcheva-Dimitrov, Rick Fuller, Igor Gonda, Hans Lundbäck, Bo Olsson and Jeffry Weers
Clive Page, ASSOCIATE EDITOR

Pharmacological Reviews January 2022, 74 (1) 48-118; DOI: https://doi.org/10.1124/pharmrev.120.000108
Open Access
The Yin and Yang of ERBB4: Tumor Suppressor and Oncoprotein
Lauren M. Lucas, Vipasha Dwivedi, Jared I. Senfeld, Richard L. Cullum, Christopher P. Mill, J. Tyler Piazza, Ianthe N. Bryant, Laura J. Cook, S. Tyler Miller, James H. Lott, Connor M. Kelley, Elizabeth L. Knerr, Jessica A. Markham, David P. Kaufmann, Megan A. Jacobi, Jianzhong Shen and David J. Riese
Eric Barker, ASSOCIATE EDITOR

Pharmacological Reviews January 2022, 74 (1) 18-47; DOI: https://doi.org/10.1124/pharmrev.121.000381
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Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease
Vincent Pons and Serge Rivest
Robert Dantzer, ASSOCIATE EDITOR

Pharmacological Reviews January 2022, 74 (1) 1-17; DOI: https://doi.org/10.1124/pharmrev.121.000400
Open Access
Aldo-Keto Reductases and Cancer Drug Resistance
Trevor M. Penning, Sravan Jonnalagadda, Paul C. Trippier and Tea Lanišnik Rižner
Michael Gottesman, ASSOCIATE EDITOR

Pharmacological Reviews July 2021, 73 (3) 1150-1171; DOI: https://doi.org/10.1124/pharmrev.120.000122
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Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors
Roger L. Papke and Nicole A. Horenstein
Habibeh Khoshbouei, ASSOCIATE EDITOR

Pharmacological Reviews July 2021, 73 (3) 1118-1149; DOI: https://doi.org/10.1124/pharmrev.120.000097
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Aiding and Abetting Anhedonia: Impact of Inflammation on the Brain and Pharmacological Implications
Michael J. Lucido, Mandy Bekhbat, David R. Goldsmith, Michael T. Treadway, Ebrahim Haroon, Jennifer C. Felger and Andrew H. Miller
Robert Dantzer, ASSOCIATE EDITOR

Pharmacological Reviews July 2021, 73 (3) 1084-1117; DOI: https://doi.org/10.1124/pharmrev.120.000043
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Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review
Ida Fredriksson, Marco Venniro, David J. Reiner, Jonathan J. Chow, Jennifer M. Bossert and Yavin Shaham
Michael Nader, ASSOCIATE EDITOR

Pharmacological Reviews July 2021, 73 (3) 1050-1083; DOI: https://doi.org/10.1124/pharmrev.120.000191
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The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors
Dean Paes, Melissa Schepers, Ben Rombaut, Daniel van den Hove, Tim Vanmierlo and Jos Prickaerts
Martin Michel, ASSOCIATE EDITOR

Pharmacological Reviews July 2021, 73 (3) 1016-1049; DOI: https://doi.org/10.1124/pharmrev.120.000273

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