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Biased Receptor Signaling in Drug Discovery
Terry Kenakin
Eric L. Barker, ASSOCIATE EDITOR

Pharmacological Reviews April 2019, 71 (2) 267-315; DOI: https://doi.org/10.1124/pr.118.016790
Open Access
Core Outcome Measures in Preclinical Assessment of Candidate Analgesics
S. Stevens Negus
Michael A. Nader, ASSOCIATE EDITOR

Pharmacological Reviews April 2019, 71 (2) 225-266; DOI: https://doi.org/10.1124/pr.118.017210
Open Access
Gut Reactions: Breaking Down Xenobiotic–Microbiome Interactions
Gerard Clarke, Kiran V. Sandhu, Brendan T. Griffin, Timothy G. Dinan, John F. Cryan and Niall P. Hyland
Charles P. France, ASSOCIATE EDITOR

Pharmacological Reviews April 2019, 71 (2) 198-224; DOI: https://doi.org/10.1124/pr.118.015768
Open Access
A Practical Review of Proteasome Pharmacology
Tiffany A. Thibaudeau and David M. Smith
Qiang Ma, ASSOCIATE EDITOR

Pharmacological Reviews April 2019, 71 (2) 170-197; DOI: https://doi.org/10.1124/pr.117.015370
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Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology
Jessie L.-S. Au, Roberto A. Abbiati, M. Guillaume Wientjes and Ze Lu
Yoshihiro Ishikawa, ASSOCIATE EDITOR

Pharmacological Reviews April 2019, 71 (2) 157-169; DOI: https://doi.org/10.1124/pr.118.016816

About Pharmacological Reviews

Pharmacological Reviews presents important review articles covering the broad spectrum of pharmacological research. Topics covered have included biochemical and cellular pharmacology, drug metabolism and disposition, renal pharmacology, neuropharmacology, behavioral pharmacology, clinical pharmacology, and toxicology. IUPHAR nomenclature reports are published here.

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Pharmacological Reviews is published continuously. Articles are added as they are ready. Quarterly issues are completed on or about the first business day of January, April, July, and October. Check this site for new content or sign up for content alerts.