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Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure
Lauren B. Arendse, A. H. Jan Danser, Marko Poglitsch, Rhian M. Touyz, John C. Burnett, Catherine Llorens-Cortes, Mario R. Ehlers and Edward D. Sturrock
Eric L. Barker, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 539-570; DOI: https://doi.org/10.1124/pr.118.017129
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Druggable Transcriptional Networks in the Human Neurogenic Epigenome
Gerald A. Higgins, Aaron M. Williams, Alex S. Ade, Hasan B. Alam and Brian D. Athey
Lori L. Isom, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 520-538; DOI: https://doi.org/10.1124/pr.119.017681
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Beyond the Ligand: Extracellular and Transcellular G Protein–Coupled Receptor Complexes in Physiology and Pharmacology
Henry A. Dunn, Cesare Orlandi and Kirill A. Martemyanov
Eric L. Barker, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 503-519; DOI: https://doi.org/10.1124/pr.119.018044
Open Access
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
Cai Read, Duuamene Nyimanu, Thomas L. Williams, David J. Huggins, Petra Sulentic, Robyn G. C. Macrae, Peiran Yang, Robert C. Glen, Janet J. Maguire and Anthony P. Davenport
Eliot H. Ohlstein, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 467-502; DOI: https://doi.org/10.1124/pr.119.017533
Open Access
Role of Voltage-Gated Sodium Channels in the Mechanism of Ether-Induced Unconsciousness
Nicholas Denomme, Jacob M. Hull and George A. Mashour
Lori L. Isom, ASSOCIATE EDITOR

Pharmacological Reviews October 2019, 71 (4) 450-466; DOI: https://doi.org/10.1124/pr.118.016592

About Pharmacological Reviews

Pharmacological Reviews presents important review articles covering the broad spectrum of pharmacological research. Topics covered have included biochemical and cellular pharmacology, drug metabolism and disposition, renal pharmacology, neuropharmacology, behavioral pharmacology, clinical pharmacology, and toxicology. IUPHAR nomenclature reports are published here.

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Pharmacological Reviews is published continuously. Articles are added as they are ready. Quarterly issues are completed on or about the first business day of January, April, July, and October. Check this site for new content or sign up for content alerts.