PT  - JOURNAL ARTICLE
AU  - Germain, Pierre
AU  - Chambon, Pierre
AU  - Eichele, Gregor
AU  - Evans, Ronald M.
AU  - Lazar, Mitchell A.
AU  - Leid, Mark
AU  - De Lera, Angel R.
AU  - Lotan, Reuben
AU  - Mangelsdorf, David J.
AU  - Gronemeyer, Hinrich
TI  - International Union of Pharmacology. LX. Retinoic Acid Receptors
AID  - 10.1124/pr.58.4.4
DP  - 2006 Dec 01
TA  - Pharmacological Reviews
PG  - 712--725
VI  - 58
IP  - 4
4099  - http://pharmrev.aspetjournals.org/content/58/4/712.short
4100  - http://pharmrev.aspetjournals.org/content/58/4/712.full
SO  - Pharmacol Rev2006 Dec 01; 58
AB  - Retinoid is a term for compounds that bind to and activate retinoic acid receptors (RARα, RARβ, and RARγ), members of the nuclear hormone receptor superfamily. The most important endogenous retinoid is all-trans-retinoic acid. Retinoids regulate a wide variety of essential biological processes, such as vertebrate embryonic morphogenesis and organogenesis, cell growth arrest, differentiation and apoptosis, and homeostasis, as well as their disorders. This review summarizes the considerable amount of knowledge generated on these receptors.