PT  - JOURNAL ARTICLE
AU  - David D. Moore
AU  - Shigeaki Kato
AU  - Wen Xie
AU  - David J. Mangelsdorf
AU  - Daniel R. Schmidt
AU  - Rui Xiao
AU  - Steven A. Kliewer
TI  - International Union of Pharmacology. LXII. The NR1H and NR1I Receptors: Constitutive Androstane Receptor, Pregnene X Receptor, Farnesoid X Receptor α, Farnesoid X Receptor β, Liver X Receptor α, Liver X Receptor β, and Vitamin D Receptor
AID  - 10.1124/pr.58.4.6
DP  - 2006 Dec 01
TA  - Pharmacological Reviews
PG  - 742--759
VI  - 58
IP  - 4
4099  - http://pharmrev.aspetjournals.org/content/58/4/742.short
4100  - http://pharmrev.aspetjournals.org/content/58/4/742.full
SO  - Pharmacol Rev2006 Dec 01; 58
AB  - The nuclear receptors of the NR1H and NR1I subgroups include the constitutive androstane receptor, pregnane X receptor, farnesoid X receptors, liver X receptors, and vitamin D receptor. The newly emerging functions of these related receptors are under the control of metabolic pathways, including metabolism of xenobiotics, bile acids, cholesterol, and calcium. This review summarizes results of structural, pharmacologic, and genetic studies of these receptors.