PT  - JOURNAL ARTICLE
AU  - JEAN-LOUIS PARROT
TI  - THE PLACE OF HISTAMINE IN NEUROHUMORAL TRANSMISSION
DP  - 1954 Mar 01
TA  - Pharmacological Reviews
PG  - 119--122
VI  - 6
IP  - 1
4099  - http://pharmrev.aspetjournals.org/content/6/1/119.short
4100  - http://pharmrev.aspetjournals.org/content/6/1/119.full
SO  - Pharmacol Rev1954 Mar 01; 6
AB  - 1. The mediator of the vasodilator fibres of the posterior roots seems to be neither histamine nor acetylcholine. 2. After irritation of the skin, histamine released by injured cells is able to stimulate peripheral endings of the vasodilator fibres and elicit a vasodilator axon reflex. 3. In the same way, histamine released from the skin by certain aggressions can stimulate the peripheral origin of certain sensory nerves and elicit painful sensations such as, possibly, burning and, very probably, itching.