RT Journal Article
SR Electronic
T1 THE PLACE OF HISTAMINE IN NEUROHUMORAL TRANSMISSION
JF Pharmacological Reviews
JO Pharmacol Rev
FD American Society for Pharmacology and Experimental Therapeutics
SP 119
OP 122
VO 6
IS 1
A1 JEAN-LOUIS PARROT
YR 1954
UL http://pharmrev.aspetjournals.org/content/6/1/119.abstract
AB 1. The mediator of the vasodilator fibres of the posterior roots seems to be neither histamine nor acetylcholine. 2. After irritation of the skin, histamine released by injured cells is able to stimulate peripheral endings of the vasodilator fibres and elicit a vasodilator axon reflex. 3. In the same way, histamine released from the skin by certain aggressions can stimulate the peripheral origin of certain sensory nerves and elicit painful sensations such as, possibly, burning and, very probably, itching.