TABLE 3

Simplified genotype-phenotype relationship for CYP2D6

Genotype (Allele Combination)Phenotype
(wt/wt)naUM
wt/wtEM
wt/*xEM
*x/*xPM

  • wt, active wild-type; UM, ultrarapid metabolizer; *x, inactive.

  • ↵a n ≥ 2.