Table 1

Drugs metabolized by blood cells in humans

CompoundReference
Acetylsalicylic acid1-b Harris and Riegelman (1967)
Rylance et al. (1981)
Costello et al. (1984)
N-Acetylcystein1-b Keith et al. (1984)
4-Aminophenol1-b Eckert (1988)
Azathioprine1-b Chalmers et al. (1967)
Ellion and Hitchings (1975)
Bunolol1-b Leinweber and DiCarlo (1974)
Captopril1-b Keith et al. (1984)
Chlorpromazine1-b Traficante et al. (1979)
Dapsone1-b , 1-c Drayer et al. (1974)
Daunorubicin1-b , 1-c Huffman and Bachur (1972)
Dehydroepiandrosterone1-b Morsches et al. (1981)
Didanosin1-b Back et al. (1992)
Barry et al. (1993)
Dopamine1-b Männl and Hempel (1972)
Ratge et al. (1991)
Epinephrine1-b Männl and Hempel (1972)
Dannon and Sapira (1972)
Esmolol1-b Quon and Stampfli (1985)
Gorczynski (1985)
Estradiol1-b, Estrone1-b Repke and Markwardt (1954)
Migeon et al. (1962)
Jacobsohn et al. (1975)
Etoposide1-b Loo et al. (1987)
5-Fluorouracil1-a Schaaf et al. (1986)
Haloperidol1-b Inaba et al. (1989)
Chan et al. (1992)
Heroin1-b Owen and Nakatsu (1983)
Insulin1-b Gambhir et al. (1981)
Nerurkar and Gambhir (1981)
Isoproterenol1-b, isosorbide Männl and Hempel (1972)
 dinitrate1-b , 1-d Bennett et al. (1983)
Bennett et al. (1985)
LY 2178961-b Bonate and Peyton (1995)
6-mercaptopurine1-b Weinshilboum and Sladek (1980)
Pazmiño et al. (1980)
Rostami-Hodjegan et al. (1995)
Misonidazole1-b Loo et al. (1987)
Nitroglycerin1-a , 1-b, metabolites1-a , 1-b Armstrong et al. (1980)
Noonan and Benet (1982)
Sokoloski et al. (1983)
Bennett et al. (1985)
Cossum and Roberts (1985)
Chong and Fung (1989)
Norepinephrine1-b Axelrod and Cohn (1971)
Männl and Hempel (1972)
Ratge et al. (1991)
Para-aminobenzoic acid1-b , 1-c Blondheim (1955)
Motulski and Steinmann (1962)
Mandelbaum-Shavit and Blondheim (1981)
Para-aminosalicylic acid1-b , 1-c Motulski and Steinmann (1962)
Drayer et al. (1974)
Penicillamin1-b Keith et al. (1985)
Pentaerythritol tetranitrate1-b DiCarlo et al. (1965)
Pentoxyphillin1-a Bryce et al. (1980)
Ings et al. (1992)
Procainamide1-a Drayer et al. (1974)
Chen et al. (1983)
Procaine1-a , 1-c Calvo et al. (1980)
Progesterone1-b Van der Molen and Groen (1968)
Ribavirin1-b Zimmerman and Deeprose (1978)
Page and Connor (1990)
Sulfanilamide1-b , 1-c Blondheim (1955)
Testosterone1-b Van der Molen and Groen (1968)
Mulder et al. (1972)
Thioguanine1-b Lennard and Maddocks (1983)
Thiospirolactone1-b Keith et al. (1984)
  • 1-a Blood cells.

  • 1-b Red blood cells.

  • 1-c White blood cells.

  • 1-d Gender-related difference in rate of metabolism.