Radioactive ligands used to label the glycineB site of the NMDA receptor (data for hippocampal/cortical or hemisphere membrane preparations)
| Radiolabeled ligand | Kd (nM) | Bmax (pmol/mg of protein) | References |
|---|---|---|---|
| [3H]5,7-diCl-KYN | 69 | 14.5 | Baronet al., 1991 |
| [3H]L-689,560 | 2.9 | 4.2 | Grimwood et al., 1992 |
| [3H]MDL 105,519 | 3.8 | 12.1 | Baronet al., 1996a |
| [3H]ACPC | 129 (H)4-a, 7300 (L) | 2.3 (H), 20 (L) | Popik et al.,1995 |
| d-[3H]Serine (cortex) | 355 | 5 | Danysz et al., 1990 |
| [3H]Glycine (cortex) | 126 | 3.4 | Kishimoto et al., 1981 |
↵4-a H, high affinity site; L, low affinity site.