Table 10

Distribution of [3H]CCK-4 binding to CCK receptors in the rat brain

Frontal cortexSeptal region
 Layers I–III++ Septum+
 Layer III, medial part++++ Bed nucleus of the stria terminalis++
 Layer IV+++  Septohippocampal nucleus++
 Layer V++Hippocampus
 Layer VI+++  Subiculum+++
Frontoparietal motor cortex CA1–CA3+
 Layers I–III++ Dentate gyrus+++
 Layer IV+++Amygdala
 Layers V, VI++ Lateral nucleus++
Frontoparietal somatosensory cortex Posteromedial nucleus++
 Layers I–III++ Amygdalo-hippocampal area++
 Layer IV+++Hypothalamus
 Layers V, VI++ Ventromedial nucleus+++
Striate cortex Paraventricular nucleus+++
 Layers I–V+++ Supraoptic nucleus+++
Temporal cortex (auditory area)Thalamus
 Layers I–III+++ Lateral habenula+
 Layer IV++++ Paraventricular nucleus++
 Layers V, VI+++ Reticular thalamic nucleus+++
 Zona incerta+
 Cingulate cortex, layer III++++ Midbrain
 Retrosplenial cortex++++  Superior++
 Entorhinal cortex+++ Substantia nigra++
 Endopyriform nucleus++++ Periacqueductal gray matter+
Olfactory-system
 Olfactory bulbs
  External plexiform layer+++
  Glomerular layer+++
 Anterior olfactory nucleus++
 Olfactory tubercule+++
 Primary olfactory cortex (superficial layer)++++
Basal ganglia
 Striatum
  Head+++
  Body+++
  Tail+
 Nucleus accumbens
  Anterior part++++
  Posterior part+
 Globus pallidus+

  • ++++, high level; +++, moderate level; ++, low level; +, very low level.