Table 4

Ligand and leukocyte specificities for human chemokine receptors

Thymocytes+++++
CD34+cell++
NK cell+++++
B lymphocyte++++++++
T lymphocyte+++++++++++++++
Immature DC+++++
Mature DC+++
Red blood cell+
Macrophage++++++++
Basophil++
Eosinophil+++
Neutrophil+++++
Platelets+
CXCR1CXCR2CXCR3CXCR4CXCR5CCR1CCR2CCR3CCR4CCR5CCR6CCR7CCR8CCR9XCR1CX3CR1DuffyD6
CXCL1/Groα++++++
CXCL2/Groβ+++
CXCL3/Groγ+++
CXCL4/PF-4
CXCL5/ENA-78++++
CXCL6/GCP-2++
CXCL7/NAP-2++++++
CXCL8/IL-8+++++++++
CXCL9/Mig+++
CXCL10/γIP-10+++
CXCL11/I-TAC+++
CXCL12/SDF-1+++
CXCL13/BCA1+++
CXCL14/BRAK
CCL1/I-309+++
CCL2/MCP-1+++++++++
CCL3/MIP-1α++++++
CCL4/MIP-1β++++++++
CCL5/RANTES++++++++++++++
CCL7/MCP-3++++++++++
CCL8/MCP-2+++++++++++++
CCL11/eotaxin++++++
CCL13/MCP-4++++++++++++
CCL14/HCC-1++++++
CCL15/Lkn-1++++++
CCL16/LEC
CCL17/TARC++++
CCL18/PARC
CCL19/ELC+++
CCL20/LARC+++
CCL21/SLC++++
CCL22/MDC+++
CCL23/MPIF-1+++
CCL24/MPIF-2+++
CCL25/TECK+++
CCL26/eotaxin-3++
XCL1/lymphotactin+++
XCL2/lymphotactin+++
CX3CL1/fractalkine+++

Note that leukocyte distribution is based mainly on in vitro studies, which have in some cases conflicted. See text for details and references.