Extracellular concentration of drugs in the plasma and cerebrospinal fluid
| Drug | Concentration | ||
|---|---|---|---|
| Plasma | Cerebrospinal Fluid | Reference | |
| μM | |||
| Nicotine | 0.4–4.5 | Zevin et al., 1998 | |
| Imipramine | 1–2 | Besret et al., 1996 | |
| Citalopram | 1 | Hyttel, 1982 | |
| Desmethylimipramine | 2 | 0.1 | Muscettola et al., 1978 |
| Fluoxetine | 1 | Pato et al., 1991 | |