Transmitter | Tissue Preparation or Brain Area | Transmitter-Releasing Stimulus | References |
---|---|---|---|
In vivo | |||
ACh6-a | Rat medial-prefrontal cortex | None | Gessa et al., 1998a |
Rat hippocampus | None | —6-b | |
GABA6-c | Rat striatum | None | Tersigni and Rosenberg, 1996 |
In vitro | |||
ACh | Rat hippocampal slices | ES | —6-d |
Rat hippocampal & frontal cortical synaptosomes | K+ or Ca2+ | Gifford et al., 2000 | |
Mouse hippocampal or cerebrocortical slices | ES or Ca2+ | —6-e | |
Guinea pig intestinal tissue (MPLM) | ES | —6-f | |
NA | Guinea pig cerebrocortical slices | ES | Schlicker et al., 1997 |
Human and guinea pig hippocampal slices | ES or Ca2+ | Schlicker et al., 1997 | |
Guinea pig hippocampal slices | NMDA or kainate | Kathmann et al., 1999a | |
Guinea pig hypothalamic slices | ES | Schlicker et al., 1997 | |
Guinea pig cerebellar slices | ES | Schlicker et al., 1997 | |
Guinea pig retinal discs | ES or Ca2+ | Schlicker et al., 1996 | |
Guinea pig bronchial slices | ES | Vizi et al., 2001 | |
Human atrial appendage segments | ES | Molderings et al., 1999 | |
Rat atria | ES | Ishac et al., 1996 | |
Rat heart | ES | Kurihara et al., 2001 | |
Rat vas deferens | ES | Ishac et al., 1996 | |
Mouse vas deferens | ES | Trendelenburg et al., 2000 | |
Mouse cultured sympathetic neurons | ES | Göbel et al., 2000 | |
DA | Rat striatal slices | NMDA | Kathmann et al., 1999a |
Rat striatal slices | ES | Cadogan et al., 1997 | |
Guinea pig retinal discs | ES | Schlicker et al., 1996 | |
5-HT | Mouse cerebrocortical slices | ES or Ca2+ | Nakazi et al., 2000 |
Mouse hypothalamic slices | ES | Kathmann et al., 1999b | |
GABA | Human hippocampal slices | ES | Katona et al., 2000 |
Rat hippocampal slices | ES | Katona et al., 1999 | |
GABA6-c | Rat or mouse hippocampal slices | ES | —6-g |
Slices of rat or mouse amygdala (BLC) | ES | Katona et al., 2001 | |
1y cultures of neonatal rat hippocampal cells | None | Irving et al., 2000 | |
1y cultures of neonatal rat hippocampal cells | ES | Ohno-Shosaku et al., 2001 | |
Rat striatal slices | ES | Szabo et al., 1998 | |
Rat midbrain slices (SNR) | ES | —6-h | |
Rat brain slices (RVM) | ES | Vaughan et al., 1999 | |
Rat cerebellar slices | None | Takahashi and Linden, 2000 | |
Rat cerebellar slices | ES | Kreitzer and Regehr, 2001b | |
Rat brain slices (PAG) | ES | Vaughan et al., 2000 | |
Rat brain slices (shell region of NAc) | ES | Hoffman and Lupica, 2001 | |
Mouse brain slices (NAc) | ES | Manzoni and Bockaert, 2001 | |
Rat spinal trigeminal nucleus pars caudalis (SG) | ES | Jennings et al., 2001 | |
Guinea pig intestinal tissue (MPLM) | Ethylenediamine | Begg et al., 2002 | |
Glu6-c | Rat prefrontal cortical slices | ES | Auclair et al., 2000 |
Rat brain slices (PAG) | ES | Vaughan et al., 2000 | |
Mouse brain slices (NAc) | ES | Robbe et al., 2001 | |
1y cultures of rat hippocampal cells | Low [Mg2+]o | —6-i | |
1y cultures of rat hippocampal cells | ES | Sullivan, 1999 | |
Mouse hippocampal slices6-j | ES | —6-k | |
Rat or mouse cerebellar slices | ES | —6-l | |
Rat striatal slices | ES | —6-m | |
Rat midbrain slices (SNR) | ES | Szabo et al., 2000 | |
Rat spinal cord slices (SG) | ES | Morisset and Urban, 2001 | |
1y cultures of rat cerebellar granule cells | Low [Mg2+]o | Irving et al., 2001 | |
Gly6-c | Rat spinal trigeminal nucleus pars caudalis (SG) | ES | Jennings et al., 2001 |
d-Asp | 1y cultures of rat cerebellar granule cells | K+ | Breivogel et al., 1999 |
CCK | Rat hippocampal slices | K+ | Beinfeld and Connolly, 2001 |
ES, electrical stimulation; [Mg2+]o, extracellular magnesium concentration; MPLM, myenteric plexus-longitudinal muscle preparation; BLC, basolateral complex; NAc, nucleus accumbens; PAG, periaqueductal gray; RVM, rostral ventromedial medulla; SG, substantia gelatinosa; SNR, substantia nigra pars reticulata; ACh, acetylcholine; DA, dopamine; d-Asp,d-aspartate; NA, noradrenaline; 1y, primary.
↵6-a ACh collected by microdialysis.
↵6-b Gessa et al., 1997, 1998a; Carta et al., 1998; Nava et al., 2000, 2001.
↵6-c Indirect electrophysiological evidence for decreased transmitter release: in some of these investigations, there was also evidence that cannabinoids inhibited spontaneous as well as evoked release of GABA or Glu.
↵6-d Gifford and Ashby, 1996; Gifford et al., 1997a,b; 1999; Kathmann et al., 2001a.
↵6-e Nakazi et al., 2000; Kathmann et al., 2001a,b.
↵6-f Pertwee et al., 1996; Coutts and Pertwee, 1997; Mang et al., 2001.
↵6-g Hájos et al., 2000, 2001;Hoffman and Lupica, 2000; Wilson and Nicoll, 2001.
↵6-h Chan and Yung, 1998; Chan et al., 1998.
↵6-i Shen et al., 1996; Shen and Thayer, 1998a,b; 1999.
↵6-j Signs ofR-(+)-WIN55212-induced inhibition of glutamate release have been observed in tissue from both wild-type and CB1 −/− mice.
↵6-k Misner and Sullivan, 1999;Hájos et al., 2001.
↵6-l Lévénès et al., 1998; Kreitzer and Regehr, 2001a; Maejima et al., 2001.
↵6-m Gerdeman and Lovinger, 2001; Huang et al., 2001.