Table 5
Meaning of observed affinity (K App ), (fractional) response, and EC50 in the quaternary complex model under different limiting conditions
| [B] = 0 | [G] = 05-a | |
|---|---|---|
| KApp |
|
|
| Response |
|
|
| EC50 |
|
|
↵5-a In the absence of [G], the expression for response is more accurately defined as the stimulus and is equal to ([R*] + [AR*] + [BR*] + [AR*B])/[R]T.