Affinity and cooperativity estimates for the allosteric modulator, N-chloromethylbrucine, at the five subtypes of muscarinic acetylcholine receptors
| Subtype | log[KA−1] | α |
|---|---|---|
| M1 | 4.38 | 0.45 |
| M2 | 4.22 | 0.094 |
| M3 | 3.66 | 3.26 |
| M4 | 4.32 | 1.03 |
| M5 | 3.66 | 0.055 |
Data from Lazareno et al., 1998.