K2P15.1 channels

Channel name K2P15.1
Description Two-pore domain potassium channel subunit
Other names KCNK15, TASK-5,1,2 KT3.33
Molecular information Human: 330aa, NM_022358, chr0.20q12, KCNK15, GeneID: 60598, PMID: 114098811
Rat: 318aa, AF467250
Mouse: 324aa, XM_141526
Associated subunits Not established
Functional assays Electrophysiological
Current Not established (see “Comments”)
Conductance Not established
Ion selectivity Not established
Activation Not established
Inactivation Not established
Activators None
Gating inhibitors None
Blockers None
Radioligands None
Channel distribution Brain, heart, lung, kidney, liver, pancreas, adrenal gland, thyroid, salivary gland, placenta
Physiological functions Not established
Mutations and pathophysiology Not established
Pharmacological significance Not established
Comments The product of this gene has not yet been shown to be a functional channel
  • aa, amino acids; chr., chromosome.

  • 1. Kim D and Gnatenco C (2001) TASK-5, a new member of the tandem-pore K(+) channel family. Biochem Biophys Res Commun 284:923-930

  • 2. Ashmole I, Goodwin PA, and Stanfield PR (2001) TASK-5, a novel member of the tandem pore K+ channel family. Pflueg Arch Eur J Physiol 442:828-833

  • 3. Vega-Saenz de Miera E, Lau DH, Zhadina M, Pountney D, Coetzee WA, and Rudy B (2001) KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related toTASK-1. J Neurophysiol 86:130-142