Channel name | TRPML31 |
Description | Nonselective cation channel subunit |
Other names | MCOLN3, mucolipin 3 |
Molecular information | Human unigene: Hs0.535239, chr. 1p22.3 |
Mouse unigene: Mm0.114683, chr. 3 | |
Associated subunits | Not established |
Functional assays | Patch-clamp, calcium imaging |
Current | Not established |
Conductance | Not established |
Ion selectivity | Not established |
Activation | Not established |
Inactivation | Not established |
Activators | Not established |
Gating inhibitors | Not established |
Blockers | Not established |
Radioligands | Not established |
Channel distribution | Widely expressed |
Physiological functions | Hair cell, stereocilia maturation |
Mutations and pathophysiology | Not established |
Comments | Va |
chr., chromosome; Va, Varitint-waddler mouse.
↵1. Di Palma F, Belyantseva IA, Kim HJ, Vogt TF, Kachar B, and Noben-Trauth K (2002) Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. Proc Natl Acad Sci USA 99:14994-14999