Drug Combinations | DRIa Values at: | CIb Values at: | ||||||
---|---|---|---|---|---|---|---|---|
EC50 | EC75 | EC90 | EC95 | EC50 | EC75 | EC90 | EC95 | |
AZT + | 3.87 | 3.85 | 3.83 | 3.82 | 0.455 | 0.451 | 0.446 | 0.444 |
NEV (1:40) | 5.09 | 5.24 | 5.40 | 5.50 | ||||
AZT + | 5.43 | 5.12 | 4.89 | 4.74 | ||||
NEV + | 7.08 | 6.97 | 6.86 | 6.79 | 0.368 | 0.371 | 0.377 | 0.381 |
IFN (1:40:16) | 24.36 | 30.76 | 38.90 | 45.57 | ||||
AZT + | 3.80 | 4.14 | 4.33 | 4.56 | ||||
NEV + | 5.06 | 5.57 | 6.14 | 6.55 | 0.602 | 0.574 | 0.548 | 0.532 |
ABT-538 (1:40:4) | 6.87 | 6.61 | 6.38 | 6.20 | ||||
AZT + | 6.0 | 6.0 | 6.0 | 6.05 | ||||
NEV + | 7.81 | 8.16 | 8.52 | 8.79 | 0.426 | 0.420 | 0.418 | 0.416 |
ABT-538 + | 10.61 | 9.68 | 8.87 | 8.33 | ||||
IFN (1:40:4:16) | 26.89 | 36.00 | 48.26 | 58.93 | ||||
AZT + | 5.18 | 5.80 | 6.29 | 6.62 | ||||
NEV + | 6.99 | 7.84 | 8.79 | 9.51 | ||||
ABT-538 + | 9.50 | 9.28 | 9.13 | 9.00 | 0.609 | 0.539 | 0.485 | 0.455 |
IFN + | 23.95 | 34.65 | 49.83 | 63.78 | ||||
DDI (1:40:4:16:1600) | 7.90 | 9.77 | 12.09 | 13.97 |