Cannabinoid receptor antagonist
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Rimonabant | Accomplia | 20 mg/day | N.A. | Depressive symptoms, nausea, diarrhea; approved by the Center for Proprietary Medicinal Products in Europe-approval by FDA pending |
Pancreatic lipase inhibitor
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Orlistat | Xenical | 120 mg t.i.d. before meals | None | Daily vitamin pill in the evening; may interact with cyclosporine |
Norepinephrine-serotonin reuptake inhibitor
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Sibutramine | Meridia | 5-15 mg/day | IV | Raises blood pressure slightly; do not use with monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, sumatriptan, dihydroergotamine, meperidine, methadone, pentazocine, fentanyl, lithium, or tryptophan |
| Reductil | | | |
Sympathomimetic drugs
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Diethylpropion | Tenuate | 25 mg t.i.d. | IV | All sympathomimetic drugs are similar; do not use with monoamine oxidase inhibitors, guanethidine, alcohol, sibutramine, or tricyclic antidepressants |
| Tepanil | 25 mg t.i.d. | | |
| Tenuate | 75 mg in A.M. | | |
| Dospan | | | |
Phentermine | Standard release: | 18.75-37.5 mg t.i.d. | IV | |
| Adipex-P | | | |
| Fastin | | | |
| Obenix | | | |
| Oby-Cap | | | |
| Oby-Trim | | | |
| Zantryl | | | |
| Slow release: | 15-30 mg/day in A.M. | | |
| Ionamin | | | |
Benzphetamine | Didrex | 25-50 mg 1-3 times/day | III | All sympathomimetic drugs are similar; do not use with monoamine oxidase inhibitors, guanethidine, alcohol, sibutramine, or tricyclic antidepressants |
Phendimetrazine | Standard release: | 35 mg t.i.d. before meals | III | All sympathomimetic drugs are similar; do not use with monoamine oxidase inhibitors, guanethidine, alcohol, sibutramine, or tricyclic antidepressants |
| Bontril PDM | | | |
| Plegine | | | |
| X-Trozine | | | |
| Slow release: | 105 mg/day in A.M. | | |
| Bontril | | | |
| Prelu-2 | | | |
| X-Trozine |
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