TABLE 4

Carboxyl-terminal protein binding partners for NMDA and delta receptor subunits

Entries indicate data supporting direct interactions between the indicated protein and glutamate receptor subunit.

ProteinGluN1GluN1GluN2AGluN2BGluN2C,DGluN3AGluD1GluD2
DelphilinPDZY2H,coIP,IHC1
LIN7PDZcoIP,IHC2
nPISTPDZY2H,coIP,IHC3Y2H,coIP,IHC3
PICOIPK1PDZY2H,coIP,IHC4
PSD93PDZY2H,coIP5Y2H,coIP5
PSD95PDZY2H6Y2H6,7Y2H6,7Y2H,coIP5Y2H,coIP5
SAP97PDZY2H7Y2H7Y2H6Y2H,coIP5Y2H,coIP5
SAP102PDZcoIP8,9
Shank1PDZY2H,coIP,IHC10
Shank2PDZY2H,coIP,IHC10
S-SCAMPDZY2H,coIP,IHC11Y2H,coIP,IHC11Y2H,coIP,IHC12
α-actinin-2CytoskeletalY2H,coIP,IHC13Y2H,coIP,IHC13
EMAPCytoskeletalY2H14Y2H14
MAP1SCytoskeletalY2H,coIP,IHC15
PlectinScaffoldY2H16
RACK1ScaffoldcoIP,EP17
SpectrinScaffoldY2H,coIP,IHC18
AP2AdaptorY2H,IHC,EP19,20Y2H,coIP,EP19,21
AP4AdaptorY2H,coIP,IHC22
PACSIN1AdaptorY2H,coIP,EP23
CalmodulinCa2+ sensorcoIP,EP24
CARP1Other25Y2H16
COPIIOther25coIP,IHC26
GPS2Other25Y2H16
SALM1Other25Y2H,coIP,IHC27
  • coIP, coimmunoprecipitation or pull-down assay; EP, electrophysiology; IHC, immunohistochemistry; Y2H, yeast two-hybrid.

  • 1 Miyagi et al. (2002).

  • 2 Jo et al. (1999).

  • 3 Yue et al. (2002).

  • 4 Yawata et al. (2006).

  • 5 Roche et al. (1999).

  • 6 Kornau et al. (1995).

  • 7 Niethammer et al. (1996).

  • 8 Müller et al. (1996).

  • 9 Sans et al. (2003).

  • 10 Uemura et al. (2004).

  • 11 Hirao et al. (1998).

  • 12 Yap et al. (2003a).

  • 13 Wyszynski et al. (1997).

  • 14 Ly et al. (2002).

  • 15 Eriksson et al. (2007b).

  • 16 Eriksson et al. (2007a).

  • 17 Yaka et al. (2002).

  • 18 Hirai and Matsuda (1999).

  • 19 Lavezzari et al. (2004).

  • 20 Vissel et al. (2001).

  • 21 Prybylowski et al. (2005).

  • 22 Yap et al. (2003b).

  • 23 Pérez-Otaño et al. (2006).

  • 24 Ehlers et al. (1996).

  • 25 Synaptic transmembrane proteins, signaling proteins, ubiquitin-like proteins, or transport regulatory proteins.

  • 26 Mu et al. (2003).

  • 27 Wang et al. (2006).