Summary of hot plate antinociception and antinociceptive tolerance responses in mice deficient in individual GRKs in response to short-term morphine and fentanyl treatment

Hot plate antinociception
Hot plate antinociceptive tolerance
  • =, equivalent to wild type (WT) response at 10 mg/kg s.c.; ↓, significant decrease in response; N.D., not determined; HT, heterozygote.

  • a Bohn et al., 2004.

  • b Terman et al., 2004.

  • c Raehal and Bohn, 2011.

  • d K. Raehal and L. Bohn, unpublished observations.