Summary of hot plate antinociceptive responses in mice lacking β-arrestin1 or β-arrestin2 in response to different opioid agonists

Hot plate antinociception
Hot plate antinociceptive tolerance
  • =, equivalent to wild type (WT) response at 10 mg/kg s.c.; ↑, significant increase in response; ↓, significant decrease in response; N.D., not determined.

  • a Bohn et al., 2004.

  • b Bohn et al., 1999.

  • c Bohn et al., 2000.

  • d Raehal and Bohn, 2011.