Biologic functions demonstrated to be influenced by FICZ
| Biologic End Point | References | |
|---|---|---|
| In Vitro | In Vivo | |
| Antitumor activity | Shin et al., 2013 | |
| Cell growth and expression of growth factor genes | Du et al., 2005; Fritsche et al., 2007; Kostyuk et al., 2012; John et al., 2013 | Smith et al., 2013 |
| Circadian rhythmicity | Mukai and Tischkau, 2007 | |
| Expression of AhR target genes | Wei et al., 2000; Oberg et al., 2005; Sciullo et al., 2008; Nair et al., 2009; Wincent et al., 2009; Lee et al., 2010; Luecke et al., 2010; Mohammadi-Bardbori et al., 2012; Rico-Leo et al., 2013; Sumida et al., 2013 | Jönsson et al., 2009; Laub et al., 2010; Wincent et al., 2012; Odio et al., 2013 |
| Genome rearrangement | Okudaira et al., 2010, 2013 | |
| Immune response | Apetoh et al., 2010; Bankoti et al., 2010 | Quintana et al., 2008; Veldhoen et al., 2008; Martin et al., 2009; Monteleone et al., 2011; Jeong et al., 2012; Pauly et al., 2012; Qiu et al., 2012; Sibilano et al., 2012; Duarte et al., 2013; Wheeler et al., 2013; Zhou et al., 2013 |
| Nuclear receptor cross-talk | Ekins et al., 2008; Reschly et al., 2008; Bunaciu and Yen, 2013 | |